老年急性冠脉综合征患者罪犯病变血管衰减斑块特点的研究  被引量:2

Characteristics of attenuated plaque in culprit lesions for acute coronary syndrome in elderly patients

在线阅读下载全文

作  者:李旭东[1] 路雯[1] 李明哲[1] 吴强[1] 王临光[1] 黄宜杰 

机构地区:[1]徐州市中心医院心内科,221009

出  处:《中华老年医学杂志》2015年第12期1326-1329,共4页Chinese Journal of Geriatrics

摘  要:目的探讨老年急性冠脉综合征(ACS)患者的衰减斑块特点。方法2013年1月至2014年12月期间符合条件的166例ACS患者为研究对象。记录一般临床资料、冠脉造影血管病变情况和罪犯斑块的血管内超声特点,主要包括有无衰减斑块、最大衰减回声弧度、血管外弹力膜面积、管腔面积、斑块面积,计算斑块负荷和重塑指数。结果与非老年组相比老年组多支冠脉病变的比例较高(50.0%和35.1%,X2=6.525,P=0.038),衰减斑块较多(62.0%和45.9%,x2=4.245,P=0.039),最大衰减回声弧度[(142±80)°和(115±54)°,t=5.254,P=0.0003、斑块面积[(14.2±3.9)mm^2和(12.3±4.1)mm^2t=2.325,P=0.0223、斑块负荷[(81.1±14.2)%和(76.4±13.5)%,t=2.025,P=0.0423和重塑指数[(1.19±0.17)和(1.09±0.13),t=4.245,P=0.031]较大。结论老年ACS患者的发病与不稳定斑块的关系更为密切,加强稳定斑块的治疗措施将有助于老年ACS的防治。Objective To explore the characteristics of attenuated plaque (AP) in culprit lesions for acute coronary syndrome (ACS) in elderly patients. Methods This study included 166 ACS patients meeting the conditions from Jan. 1, 2013 to Sep. 31, 2014. Clinical data, vascular lesions determined by coronary angiography and intravenous ultrasound (IVUS)-demonstrated characteristics of culprit plaque, which included presence of AP, maximum attenuation arc, extravascular elastic membrane area, lumen area, plaque area, plaque burden and remodeling index, were recorded. Results Compared with non-elderly group, elderly group had a higher proportion of multiple coronary-artery lesions (50.0% w 35.1%, )z : 6. 525, P=0. 038), more attenuation plaques (62.0% w 45.9%, X2=4. 245, P=0. 039), a larger maximum attenuation arc((142±80)°vs. (115±54)°, t=5.254, P=0.000], larger plaque area((14.2±3.9)mm2 vs (12.3±4.1)mme, t 2.325, P=0.022], more plaque burden ((81.1±14.2)% vs(76.4±13.5)%, t=2.025, P~ 0.0423 and higher remodeling index ((1.19+0.17) vs. (1.09±0.13), t=4.245, P=0.0313. Conclusions The onset of ACS is more closely related with the unstable plaque in elderly patients, and strengthening the measures for plaque stabilization will be helpful in the prevention and treatment of ACS in the elderly.

关 键 词:急性冠状动脉综合征 冠状血管造影术 超声检查 衰减斑块 

分 类 号:R541.4[医药卫生—心血管疾病]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象