超声引导下外科微创封堵治疗巨大房间隔缺损的临床研究  

Clinical Study on the Minimally Invasive Surgical Treatment of Minimally Invasive Surgical Closure Treatment Guided by Ultrasound in the Treatment of Patients with Large Atrial Septal Defect

作　　者：任明明[1] 韩振[1] 闵生辉[1] 冯钢[1] 许志锋[1] 陈立波[1] 

机构地区：[1]北京大学深圳医院,广东深圳518036

出　　处：《中国医学创新》2015年第31期42-45,共4页Medical Innovation of China

基　　金：深圳市卫计委立项(201303023)

摘　　要：目的:研究及分析超声引导下外科微创封堵治疗巨大房间隔缺损的临床效果。方法:选取2013年4月-2015年2月于本院进行治疗的40例巨大房间隔缺损患者为研究对象,将其按随机数字表法随机分为A组(微创封堵治疗)20例和B组(常规手术治疗)20例,然后将两组患者的手术时间、术后住院时间、输血情况、并发症发生率、住院费用、切口大小及手术前后的炎性因子、心脏相关指标进行比较。结果:A组的手术时间及术后住院时间均短于B组,输血率及并发症发生率低于B组,住院费用高于B组,切口小于B组,而术后不同时间点的炎性因子血清表达水平低于B组,比较差异均有统计学意义(P<0.05),而两组患者不同时间的心脏相关指标比较差异无统计学意义,但均好于术前(P<0.05)。结论:超声引导下外科微创封堵治疗巨大房间隔缺损的临床效果较好,且对于患者的炎症反应控制相对更好,更为适用于此类患者的治疗。Objective：To study and analyze the clinical effect of minimally invasive surgical treatment of minimally invasive surgical closure treatment guided by ultrasound in the treatment of patients with large atrial septal defect.Method： 40 patients with large atrial septal defect in our hospital from April 2013 to February 2015 were selected as the study objects, and they were randomly divided into group A（minimally invasive surgical closure treatment）for 20 cases and group B（conventional operation treatment）for 20 cases, then the operation time, postoperative hospitalization time, transfusion condition, complication rates, hospitalization expenses, incision size, inflammatory factors and cardiac related indexes before and after the operation of the two groups were compared.Result： The operation time and postoperative hospitalization time of the group A was shorter than that of the group B, the transfusion rate and complication rate was lower, hospitalization expenses was higher, incision size was smaller, and the inflammatory factors serum expression at different time after the operation was all lower than that of the group B （P〈0.05）, while the cardiac related indexes of the two groups at different time after the operation had no obvious differences, but that was all better than the level before the operation （P〈0.05）.Conclusion：The clinical effect of minimally invasive surgical treatment of minimally invasive surgical closure treatment guided by ultrasound in the treatment of patients with large atrial septal defect are better, and its control for the inflammatory response are relatively better, so it is more suitable for the treatment of these patients.

关 键 词：超声引导下外科微创封堵治疗 巨大房间隔缺损 临床效果 炎症反应 

分 类 号：R541.1[医药卫生—心血管疾病]