2,6-二羟基-3,5-二硝基甲苯的合成新工艺  

Novel Synthesis of 2,6-Dihydroxy-3,5-dinitrotoluene

作　　者：毛婷婷[1] 陈汉庚 徐继伟[1] 胡燕红[1] 金宁人[1] 

机构地区：[1]浙江工业大学化学工程学院,浙江杭州310032 [2]浙江鼎龙集团总公司研发中心,浙江杭州310004

出　　处：《精细化工》2015年第12期1431-1436,共6页Fine Chemicals

基　　金：江苏省科技支撑计划项目(BE:2011129)~~

摘　　要：以2,6-二氯甲苯为原料经过硝化反应获得2,6-二氯-3,5-二硝基甲苯（DCDNT）,纯度为99.79%（HPLC,下同）,收率98.40%;再经亲核取代反应制得2,6-二甲氧基-3,5-二硝基甲苯（DMDNT）,纯度为96.90%,收率88.36%;最后在硫酸中酸性脱甲基反应合成MDNR,纯度为99.40%,收率93.15%。MDNR的结构经过FTIR、MS、-1HNMR定性和表征,总收率可达80%以上,操作方便。Firstly, 2,6-dichloro-3,5-dinitrotoluene （DCDNT） was prepared through the nitration of 2,6- diehlorotoluene with a purity of 99. 79% （HPLC ,the same below）and yield of 98.40%, then obtained 2,6-dimethoxy-3,5-dinitrotoluene （DMDNT）by nucleophilic substitution reaction with a purity of 96.90% , yield of 88.36% ; Finally, MDNR was successfully synthesized by the acid demethylation of DMDNT,and its purity was 99. 40% ,the yield was 93.15%. The structure of MDNR was confirmed by FTIR,MS and 1HNMR. The total yield was more than 80% with simple operation steps.

关 键 词：2 6-二羟基-3 5-二硝基甲苯 2 6-二甲氧基-3 5-二硝基甲苯 2 6-二氯-3 5-二硝基甲苯 聚对苯撑甲基苯并二口恶唑 精细化工中间体 

分 类 号：TQ316.342[化学工程—高聚物工业]