瑞芬太尼联合右美托咪定在心脏手术中的麻醉效果观察  

Observation of the Anaesthetic Effect of Remifentanil Combined with Dexmedetomidine in Operations on Heart

作　　者：钟宝琳[1] 黄桂明[1] 陈以建[1] 李优春[1] 

机构地区：[1]赣州市人民医院麻醉科,江西赣州341000

出　　处：《长江大学学报（自科版）（下旬）》2015年第12期21-22,4,共2页Journal of Yangtze University

摘　　要：目的:观察瑞芬太尼联合右美托咪定在心脏手术中的麻醉效果。方法:选择2013年4月至2015年1月开展心脏手术的100例患者,随机分为R+D组和R组。R+D组患者麻醉方式:瑞芬太尼联合右美托咪定;R组患者麻醉方式:单纯瑞芬太尼。比较麻醉效果。结果:R+D组患者麻醉不同时期MAP、HR、SpO2无明显差异,R组患者在插管后1min(T1)时MAP、SpO2、HR下降明显(P<0.05)。两组拔管时间、苏醒时间、呼吸恢复时间接近(P>0.05)。R+D组Ramsay镇静评分明显高于R组,躁动明显低于R组(P<0.05)。结论:在心脏手术中,瑞芬太尼联合右美托咪定麻醉可比单纯瑞芬太尼麻醉更好维持患者血流动力学指标的稳定,且镇静效果更佳,可减少躁动发生,值得推广。Objective:To observe the anesthetic effect of remifentanil combined with dexmedetomidine in operations on heart.Methods:100patients with cardiac surgery from April 2013 to January 2015 had been randomly divided into 2groups:the R+D group with remifentanil combined with dexmedetomidine anesthesia;the R group with pure remifentanil.The anesthetic effects had been compared.Results:In the R+D group there were no significant differences in MAP,HR,SpO2 RD of different periods;MAP,SpO2,HR of the R group decreased significantly 1min after intubation(P<0.05).The extubation time,the revival time and the respiratory recovery time of the two groups were similar(P>0.05).The Ramsay sedation scores of R+D group were significantly higher than those of R group(P<0.05).Conclusion:In cardiac surgery anesthesia by remifentanil combined with dexmedetomidine can maintain better hemodynamic stability than remifentanil only with better sedative effect and less incidence of agitation,which is worth promoting.

关 键 词：瑞芬太尼 右美托咪定 心脏手术 麻醉效果 

分 类 号：R614.24[医药卫生—麻醉学]