降钙素原与C反应蛋白对老年社区获得性肺炎患者的早期诊断价值  

The clinical research of early diagnostic value of procalcitonin and C-reactive protein on elderly patients with community-acquired pneumonia

作　　者：谭熙[1,2] 李贱 梁宗安[1] 邹朋成[2] 

机构地区：[1]四川大学华西医院呼吸内科,四川成都610041 [2]峨眉山市人民医院呼吸内科,四川峨眉山614200

出　　处：《西部医学》2015年第12期1803-1805,共3页Medical Journal of West China

基　　金：国家自然科学基金(81000877)

摘　　要：目的探讨降钙素原（PCT）与C反应蛋白（CRP）对老年社区获得性肺炎（CAP）患者的早期诊断价值。方法收集2013年1月～2014年6月我院呼吸科门诊就诊的148例老年呼吸道感染病人作为研究对象，分为CAP组38例和非CAP组110例，评价两组患者门诊治疗时CRP、PCT水平以及细菌培养的阳性率。结果CAP组与非CAP组患者首次门诊治疗时CRP、PCT水平差异有统计学意义（P〈0．05）；CAP组cRP灵敏度、特异度以及ROc面积差异均有统计学意义（均P〈0．05）。CRP与PCT诊断CAP的灵敏度、特异度以及ROc面积差异均有统计学意义（均P〈0．05）；CAP组与非CAP组血培养、痰培养阳性率差异无统计学意义（P〉0．05）。结论本研究认为，PCT早期诊断老年社区获得性肺炎灵敏度、特异度明显比cRP，对诊断老年社区获得性肺炎有重要意义。Objective To research of early diagnostic value of procalcitonin and C-reactive protein in elderly pa- tients with community-acquired pneumonia. Methods 148 elderly patients of the respiratory clinic were divided into CAP （38 cases） and non-CAP group （110 cases）. C-reactive protein, calcitonin and positive rate of bacteria culture were ob- served. Results Differences of C-reactive protein and calcitonin level CAP and non-CAP group were statistically signifi- cant （P（0.05）. The specific degree of sensitivity and ROC area difference was statistically significant （P〈0.05）. CAP group of ROC curve area difference of CRP was statistically significant （P〈0.05）. CAP and non-CAP group blood cul- ture, sputum culture positive rate difference has no statistical significance （P〉0.05）. Conclusion This study shows that calcitonin original early diagnosis elderly community-acquired pneumonia, specific degree of sensitivity c-reactive pro- tein, elderly community-acquired pneumonia has important significance to the diagnosis.

关 键 词：降钙素原 C反应蛋白 社区获得性肺炎 

分 类 号：R563.1[医药卫生—呼吸系统]