血浆置换联合血液灌流在急性有机磷农药中毒救治中的应用  

Application of Plasmapheresis Combined with Blood Perfusion to the Emergency Treatments of Organophosphorus Pesticide Poisoning

作　　者：庞辉[1] 赵曙光[2] 孙廷强[2] 陈秀芹[2] 刘静[2] 李倩倩[1] 王小影[1] 

机构地区：[1]安徽省太和县人民医院输血科,236600 [2]安徽省太和县人民医院急诊医学科,236600

出　　处：《临床输血与检验》2015年第6期484-486,共3页Journal of Clinical Transfusion and Laboratory Medicine

基　　金：2012年度阜阳市卫生局科研基金(No.2012-339-41)资助

摘　　要：目的探讨血浆置换联合血液灌流(HP)治疗急性有机磷农药中毒的疗效。方法选取60例重度有机磷农药中毒患者,分为治疗组(血浆置换联合HP组)26例和对照组(血液灌流组)34例,比较两组的观察指标(平均住院时间及胆碱酯酶活性恢复时间)。结果两组观察指标比较,差异均有统计学意义(P<0.05)。结论血浆置换与HP联合治疗能明显提高急性重度有机磷中毒的疗效。Objective To evaluate the plasmapheresis（ HP） and blood perfusion for the firsr aid treatment in acute organophosphorus pesticide poisoning. Methods Sixty cases of patients with severe organophosphorus pesticide poisoning were selected The pathients were divided into the group of treatment and group of plasmapheresis combined with blood perfusion. Twenty six cases and 34 cases of the control were observed,and observation indexes（ average length of hospital stay and cholinesterase activity-recovery time） were compared. Results The difference had statistical significance（ P〈0. 05） in the observation indexes of the two groups. Conclusion Plasmapheresis Combined with Blood Perfusion treatment may obviously improve the curative frequency for acute severe organophosphate poisoning.

关 键 词：有机磷农药中毒 血液灌流 血浆置换 胆碱酯酶 

分 类 号：R457.14[医药卫生—治疗学] R139.3[医药卫生—临床医学]