全弓置换加支架象鼻术与复合全主动脉弓置换术治疗StanfordA型夹层的对照研究  被引量:3

A case - control study on arch hybrid debranching procedure and open arch replacement on type A dissection

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作  者:龚昆梅[1] 常谦[2] 王昆华[3] 肖乐[1] 张剑[1] 郭世奎[1] 李柔刚[1] 欧阳一鸣[1] 龙亚新[1] 尚雷[1] 

机构地区:[1]云南省第一人民医院(昆明理工大学附属医院)普外科,昆明650032 [2]中国医学科学院中国协和医科大学阜外心血管病医院血管外科 [3]昆明医科大学第一附属医院普外科

出  处:《中华普通外科杂志》2015年第12期941-944,共4页Chinese Journal of General Surgery

基  金:基金项目:国家自然科学基金资助项目(81260066,81360069),云南省科技厅.昆明医科大学联合专项基金资助项目(2012FB089,2013FB199),云南省卫生领军人才项目基金资助项目(L-201205)

摘  要:目的比较深低温停循环下全弓置换加支架象鼻术与复合全主动脉弓置换术治疗A型主动脉夹层的手术效果及早期随访结果。方法2012年1月至2014年4月行深低温停循环下全主动脉弓置换加支架象鼻手术17例(深停组),同期行复合全主动脉弓置换术治疗A型主动脉夹层19例(复合组),比较2组术中体外循环结果,术后并发症,术后30d死亡率等指标。结果2组均成功完成手术,手术死亡率均为0%,深停组和复合组体外循环时间:(173±24)min和(136±28)min(P〈0.05),阻断时间:(101±12)min和(77±11)(P〈0.05),术后机械通气时间:(19±3)h和(11±3)h(P〈0.05),ICU停留时间:(3.0±0.6)d和(1.7±0.8)d(P〈0.05),截瘫:5.8%(1/17)和0%(P〈0.05),肾衰竭:11.8%(2/17)和0%(P〈0.05),脑梗死均为O%,术后30d死亡率:23.5%(4/17)和10.5%(2/19)(P〉0.05)。共随访33例,随诊率89%,随访期间2组均未发生死亡、脑梗死、肾衰竭等并发症。结论复合组较手术创伤和并发症发生明显减少,可提高术后生存率。Objective To compare arch hybrid debranching procedure and open arch replacement on type A dissection. Method From Jan 2012 to Apr 2014, 19 type A dissection cases received arch hybrid debranching procedure, and 17 cases did open total arch replacement. Results Operations were successfull in all patients. The operation time were (5.86 ±1.14) h vs. (5. 13 ± 0. 98 ) h ( P 〉 0. 05 ), bleeding amount 24hs post operation were (410 ± 170) ml vs. ( 360 ± 210 ) m] ( P 〉 0. 05 ) , intraoperative bleeding was ( 1 080 ± 190 ) ml vs. ( 950 ± 170 ) ml ( P 〉 O. 05 ) , extracorporeal circulation : ( 173 ±24 ) minvs. (136 ±28) min(P〈0.05), block time was (101± 12) vs. (77± 11) min(P 〈0.05), mechanical breath time post operation was ( 19 ± 3 ) h vs. ( 11 ± 3 ) h( P 〈 0.05 ), ICU stay time was ( 3.0 ± 0.6)dvs. (1.7±0.8)d(P〈0.05), paraplegia incidence was 5.8% (1/17) vs. 0%(P〈0.05), renal failure occurred in 11.8% (2/17) vs. 0% (P 〈 0. 05). Perioperative mortality was 23.5% (4/17) vs. 10.5%(2/19) (P 〉 0.05). 33 cases were followed up for 1 - 28 months. There were no severe complications occurred including death, cerebral infarction, renal failure. Conclusion Hybrid debranching procedure significantly reduces operational trauma and complications and improves survival rate in patients of type A dissection.

关 键 词:主动脉疾病 血管外科手术 复合全主动脉弓置换术 全弓置换加支架象鼻术 

分 类 号:R654.3[医药卫生—外科学]

 

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