腹腔镜胃旁路手术治疗2型糖尿病的疗效  

Laparoscopic Rour-en-Y gastric bypass for the treatment of type 2 diabetes mellitus

作　　者：白日星[1] 李有国[1] 秦超[1] 许峻[1] 闫文貌[1] 闫鸣[1] 汪鑫[1] 袁辉生[1] 宋茂民[1] 

机构地区：[1]首都医科大学附属北京天坛医院普通外科,100050

出　　处：《中华普通外科杂志》2015年第12期957-960,共4页Chinese Journal of General Surgery

摘　　要：目的探讨腹腔镜Roux—en-Y胃旁路术（1aparoscopicRoux—en-Ygastricbypass，LRYGB）治疗2型糖尿病的疗效及相关因素。方法回顾性分析首都医科大学附属北京天坛医院2012年4月至2013年2月问采用LRYGB治疗38例2型糖尿病患者的结果。结果本组38例2型糖尿病患者术后2年有30例（79％）不再使用降糖药物并且HbAlc〈7．0％；体质量指数≥28kg／m^2组与体质量指数〈28kg／in。组间HbAlc〈7．0％者相比差异无统计学意义（P〉0．05）；脱离降糖药物并且HbAlc≤6．5％组与HbAlc〉6．5％组间术前体质量指数、HbAlc、空腹血糖和C肽相比差异均无统计学意义（均P〉0．05），而术前糖尿病患病时间相比差异有统计学意义（P〈0．05）。结论LRYGB术是一种控制2型糖尿病血糖的有效方法，患者的患病时间影响LRYGB术后的降糖效果。Objective To evaluate the result of laparoscopic Roux-en-Y gastric bypass （LRYGB） in the treatment of type 2 diabetes mellitus. Methods This is a retrospective analysis on 38 cases over two years who were operated on by LRYGB in Beijing Tiantan Hospital from April 2012 to February 2013. Results After 2 years LRYGB procedure,30 cases （79%） are off antidiabetes drugs with HbAlc 〈7.0%. There＇s no significant difference between group BMI≥28 kg/m2 and BMI 〈28 kg/m2 in HbAlc 〈7.0% and with no more antidiabetes drug （P 〉 0. 05 ）. There＇s no significant difference between group HbA1 c ≤6. 5% without drug and group HbA1 e 〉 6.5 % without drug in preoperative BMI, HbAcl , FPG and fasting CP. But there is an obvious difference in disease duration between two groups. Conclusions LRYGB is an effective method to control glucose level in DM patients. Preoperative disease duration adversely affected postoperative glucose control.

关 键 词：糖尿病 2型 吻合术 ROUX-EN-Y 腹腔镜 

分 类 号：R656.6[医药卫生—外科学]