Study of Immunomodulating Activity of Rectal Suppositories with an Extract of Licorice Root  

作　　者：Larisa Vasilevna Yakovleva Tatiana Grigoryevna Yamykh Elena Yuryevna Koshevaya Olga Anatolievna Rukhmakova Galina Nikolaevna Melnik 

机构地区：[1]Central Scientific Research Laboratory, National University of Pharmacy, Kharkov 61002, Ukraine [2]Department of Drugs Technology, National University of Pharmacy, Kharkov 61168, Ukraine

出　　处：《Journal of Pharmacy and Pharmacology》2014年第4期277-283,共7页药剂与药理学（英文版）

摘　　要：The article is devoted to the study of the immunomodulating activity of rectal suppositories with an extract of licorice root and essential oils of chamomile and tea tree. Taking into account that medicine is intended and prescribed for children, all the experiments were performed on immature nonlinear one-month rats with weight of 60.0-80.0 g. As a result, it was found out that rectal insertion of suppositories with an extract of licorice root causes an increase in the phagocytic function of neutrophils and increases the quantity of antibodies in the spleen and titers of hemagglutinins and hemolysins in serum, that indicating on the activation of nonspecific and humoral immunity of immature animals. Moreover, the prospects of possible application of suppositories with an extract of licorice root are showed for prevention and treatment of various immunodependent diseases, viral in particular.

关 键 词：Rectal suppositories extract of licorice root immunomodulating activity STUDY 

分 类 号：R9[医药卫生—药学]