Antimicrobial Peptides from the Plants  

作　　者：Abulimiti Yili Vladimir Maksimov Qing-Ling Ma Yan-Hua Gao Olga Veshkurova Shavkat Salikhov Haji Akber Aisa 

机构地区：[1]Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry,Academy of Sciences of the People's Republic of China, Urumqi 830011, Xinjiang, PRC [2]A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent 700125, The Republic of Uzbekistan

出　　处：《Journal of Pharmacy and Pharmacology》2014年第11期627-641,共15页药剂与药理学（英文版）

摘　　要：AMPs （antimicrobial peptides） are small, mostly basic peptides that range in size from 2-9 kDa, and they are an important component of the innate defense system of plants where they are effector molecules considered to be an important defense barrier to pathogens and pests. Nine families of antimicrobial peptides have been identified in plants, including thionins, defensins, lipid transfer proteins, hevein and knotting-like peptides, four cysteine-types, and the recently reported shepherdins, snakins and cyclotides. They are part of both permanent and inducible defense barriers of plants. Transgenic overexpression of the corresponding genes leads to enhanced tolerance to pathogens, and peptide-sensitive pathogen mutants have reduced virulence. In this review, the recent studies on peptides from plant sources, including peptides isolated from indigenous medicine and edible plants of Central-Asia, are briefly discussed with a focus on their origins, antioxidant, antitumor activities and the possible mechanisms of actions in order to provide a profile of important plant peptides.

关 键 词：AMPS plant defense peptides THIONIN LTPs （lipid transfer proteins） Ib-AMPs （Impatiens balsamina antimicrobial peptides） disulfide bridge pathogen. 

分 类 号：R9[医药卫生—药学]