虫草保肾颗粒剂对慢肾衰大鼠动脉粥样硬化程度的影响分析  

Effect of Cordyceps Sinensis on the Degree of Atherosclerosis in Rats With Chronic Renal Failure

作　　者：孙洋 赵俸玉 刘娇 尹龙晶 徐佩秋 徐敢风[1] 

机构地区：[1]黑龙江省中医医院内科(干部)病房,哈尔滨150000 [2]第二炮兵总医院体检中心,北京100088

出　　处：《中国卫生标准管理》2015年第30期187-188,共2页China Health Standard Management

基　　金：黑龙江省自然科学基金面上项目;编号:H2013109

摘　　要：目的探讨虫草保肾颗粒剂对慢性肾衰大鼠动脉粥样硬化程度的影响。方法选择实验用大鼠30只,诱发大鼠粥样动脉硬化病症。将其随机分为试验组和对照组,试验组大鼠提供虫草保肾颗粒剂进行治疗,对照组则提供无菌生理盐水。分别记录两组大鼠血脂含量和动脉内膜中层厚度。结果试验组大鼠治疗后胆固醇和甘油三酯含量低于对照组(P<0.05),同时试验组大鼠动脉内膜中层厚度低于对照组(P<0.05)。结论利用虫草保肾颗粒剂可以有效缓解慢性肾衰竭大鼠的动脉粥样硬化症状,降低其体内各项血脂指标的含量。Objective To investigate the effect of Cordyceps sinensis on the degree of atherosclerosis in rats with chronic renal failure. Methods 30 rats were chosen to induce atherosclerosis. The rats were randomly divided into experimental group and control group. The rats in experimental group were treated with the granule of Chinese caterpillar fungus. The lipid content and intima media thickness in the two groups were recorded. Results The content of cholesterol and triglyceride in the experimental group was significantly lower than that in the control group（P〈0.05）,while the middle layer thickness of the rats in the experimental group was significantly lower than that in the control group（P〈0.05）. Conclusion The use of Cordyceps sinensis can effectively relieve the symptoms of atherosclerosis in chronic renal failure rats, and reduce the content of lipid in the body.

关 键 词：慢性肾衰竭 动脉粥样硬化 虫草保肾颗粒剂 

分 类 号：R318[医药卫生—生物医学工程]