1,3,5-三溴苯的合成及表征  

Synthesis and characterization of 1,3,5-bromobenzene

作　　者：胡小兵[1] 王凯传[1] 

机构地区：[1]宝鸡文理学院化学化工学院陕西省植物化学重点实验室,陕西宝鸡721013

出　　处：《化学工程师》2015年第12期48-50,共3页Chemical Engineer

基　　金：陕西省教育厅专项科研计划项目基金(14JK1041);陕西省教育厅重点实验室科研计划项目基金(14JS006);陕西省重点实验室项目(2010JS069)

摘　　要：以苯胺、溴素为主要原料,冰乙酸为溶剂,首先通过取代反应生成2,4,6-三溴苯胺,然后在无水乙醇中重结晶,得到纯净的2,4,6-三溴苯胺。然后2,4,6-三溴苯胺在Na NO_2和浓H_2SO_4的作用下,通过重氮化反应得到1,3,5-三溴苯,最后通过重结晶得到纯净的1,3,5-三溴苯。通过核磁共振氢谱和碳谱分析确定了产物为目标产物1,3,5-三溴苯。In this thesis, 1,3,5-tribromobenzene was synthesized through two steps reactions. In the first step, 2,4,6-tribromoaniline was produced by a substitution reaction using aniline and bromine as the main raw material, glacial acetic acid as solvent. And then the crude 2,4,6-tribromoaniline was recrystallized in absolute ethanol to give the pure 2,4,6-bromoaniline. In the second step, 1,3,5-tribromohenzene was synthesized by the diazotization reaction using sodium nitrite and concentrated sulfuric acid. Finally, pure 1,3,5-bromobenzene was prepared by the recrystallization of the product of the second step in glacial acetic acid and water （4：1） solution. The molecular structures of the prepared products were identified by nuclear magnetic resonance spectroscopy （NMR）. The result showed that the product was 1,3,5-tribromobenzene with a relatively high purity.

关 键 词：2 4 6-三溴苯胺 重氮化反应 1 3 5-三溴苯 

分 类 号：O625.21[理学—有机化学]