阿莫罗芬甲搽剂联合口服伊曲康唑与联合口服特比萘芬治疗甲真菌病的疗效观察  

Effect observation of Amor Luo Fenjia liniment in combined with oral itraconazole and Amor Luo Fenjia liniment combined with oral terbinafine in the treatment of onychomycosis

作　　者：陈健发 

机构地区：[1]广东省东莞市茶山医院检验科,广东东莞526638

出　　处：《吉林医学》2015年第18期4043-4045,共3页Jilin Medical Journal

摘　　要：目的:探讨甲真菌病采用阿莫罗芬甲搽剂与伊曲康唑口服联合治疗和与特比萘芬口服联合治疗效果展开对比。方法:选取甲真菌病100例,随机分组,分别为阿莫罗芬甲搽剂与伊曲康唑联用组(A组,n=50)和特比萘芬口服联用组(B组,n=50),研究两组效果对比。结果:A组近期痊愈率为26%,远期痊愈率为86%;B组近期痊愈率为24%,远期痊愈率为60%,远期痊愈率比较,差异有统计学意义(P<0.05);A组真菌清除率为86%,B组为70%。两组均无严重不良事件发生。结论:甲真菌病采用阿莫罗芬甲搽剂与伊曲康唑口服联用,可获得理想的临床效果,真菌清除率较高,具有非常重要的应用价值,可显著改善患者生存质量。Objective To study the onychomycosis by amor Luo Fenjia liniment and combination treatment with oral itraconazole and associated with oral terbinafine treatment effect comparison. Method The 100 cases of onychomycosis were selected and randomly divided into amor Luo Fenjia liniment and itraconazole together group（group A,n = 50）and amor Luo Fenjia liniment and oral terbinafine combi-nation group（group B,n = 50）. The effect of the two groups were compared. Results The recent recovery rate of group A was 26% ,the long - term cure rate was 86% ;the recent recovery rate of group B was 24% ,long - term recovery rate was 60% ,the long - term recovery rate of the two groups was statistically significant（P ﹤ 0. 05）;The fungal clearance rate of group A was 86% ,B group was 70% . Two groups had no serious adverse events. Conclusion Onychomycosis by amor Luo Fenjia liniment and oral itraconazole together,which can ob-tain ideal clinical effect,fungal clearance rate is higher,it has very important application value,can significantly improve the patients quality of life.

关 键 词：阿莫罗芬搽剂 伊曲康唑 特比奈芬 甲真菌病 

分 类 号：R756[医药卫生—皮肤病学与性病学]