不同浓度高胆红素血症患儿脑干听觉诱发电位对比分析  

THE COMPARATIVE ANALYSIS OF BRAINSTEM AUDITORY EV OKED POTENTIAL IN NEONATUS WITH DIFFERENT LEVEL OF HYPERBILIRUBINEMIA

作　　者：凌秀明[1] 唐海燕[1] 凌日宣[1] 胡礼斌 

机构地区：[1]广西钦州市第二人民医院神经电生理科,535000

出　　处：《现代电生理学杂志》2015年第4期199-202,共4页Journal of Modern Electrophysiology

摘　　要：目的:分析不同浓度胆红素血症对新生儿脑干听觉诱发电位的影响,为临床治疗和早期评估预后提供依据。方法:根据血清胆红素水平(Sb)的高低将174例患儿分成两组:甲组110例,为相对低胆红素浓度组(Sb≤342μmol/L);乙组64例,为相对高胆红素浓度组(Sb>342μmol/L)。两组进行脑干听觉诱发电位检测并进行比较。结果:174例高胆红素血症新生儿脑干听觉诱发电位共有218耳异常(62.6%),甲、乙两组比较,乙组异常率明显增高(P<0.01),甲、乙两组V波反应阀比较,差异有统计学意义(P<0.01)。结论:高胆红素血症对脑干听觉诱发电位有影响,异常率与浓度升高呈正相关。Objective： To analyse the influence of different concentrations of hyperbilirubinemia in newborn brainstem auditory evoked potential, provide the basis for clinical treatment and early assessment of prognosis. Methods： According to the level of serum bilirubin（Sb）, 174 cases were divided into two groups： group A, 110 cases（Sb ≤ 342 μmol/L） was relative low concentration of bilirubin group; Group B, 64 cases（Sb 〉342μmol/L） was relative high bilirubin concentration group.The brainstem auditory evoked potential of two groups was tested and compared. Results： The brainstem auditory evoked potential were abnormal in 218 ears.Compared with groub A, the abonrmal rate increased obriously（P 〈0.01）.There were significant differences in Ⅴ wave response domain between group A and B（P 〈0.01）. Conclusion： Hyperbilirubinemia has an effect in brainstem auditory evoked potential. The abnormal rate is positirely correlated with serum bilirubin concentration.

关 键 词：高胆红素血症 新生儿 脑干听觉诱发电位 

分 类 号：R722.1[医药卫生—儿科]