脐血总IgE水平与婴儿过敏性疾病的相关性  

Correlationbetween total IgE levels in cord blood and infants allergic diseases

作　　者：李喆[1] 彭博[2] 

机构地区：[1]内蒙古自治区巴彦淖尔市医院儿科,内蒙古临河015000 [2]内蒙古自治区巴彦淖尔市医院,内蒙古临河015000

出　　处：《四川生理科学杂志》2015年第4期188-190,共3页Sichuan Journal of Physiological Sciences

摘　　要：目的：探讨脐血总IgE水平与婴儿过敏性疾病的相关性,为临床预防和早期干预婴儿过敏性疾病提供帮助。方法：选择2013.12~2014.7于本院产科出生新生儿作为研究对象,随访婴儿至6个月大小,依据在随访期婴儿是否发生过敏性疾病,分为病例组和对照组。收集新生儿脐血2ml,离心后去血清,-20℃保存备用;应用酶联免疫（ELSIA）夹心定量检测法测定脐血总IgE值。结果：两组比较,父母过敏史（X2=8.148,P=0.004）,P值均〈0.05,有统计学意义;经秩和检验分析两组样本,脐血总IgE（Z=-4.326,P〈0.05）,P值〈0.05,有统计学意义。结论：家族过敏史是婴儿患过敏性疾病的高危因素;脐血总IgE水平升高,与婴儿过敏性疾病发生有相关性。Objective：To investigate the relationship between cord blood total IgE and infant allergic diseases.Method：The paper selected 60 newborns and their mothers based on whether suffering allergic diseases from December 2013 to July 2014,and all the patients were divided into case group and control groups according to whether suffering allergic diseases on the follow-up period.2ml cord blood were collected and reserved at–20℃ after centrifugation.Non-normally distributed measurement data between the two groups were compared with the rank sum test.Count data were compared using the chi-square test.Result：Between case group and the control group,parents allergies（X2=8.148,P=0.004）,P〈0.05,the difference was statistically significant.With Rank sum test analysis,cord blood total IgE（Z=-4.326,P〈0.05）,P〈0.05,the difference was statistically significant.Conclusion：Family history of allergies is the risk factor for infant allergic diseases;cord blood total IgE levels and the occurrence of infant allergic diseases are relevant.

关 键 词：婴儿 过敏性疾病 脐血IGE 

分 类 号：R725.9[医药卫生—儿科]