体位性睡眠呼吸暂停的临床特征研究  

Clinical features for positional sleep apnea patients

作　　者：骆剑伟[1] 曾黎[1] 许海波[1] 

机构地区：[1]浙江杭州市第三人民医院耳鼻咽喉科,310009

出　　处：《中国中西医结合耳鼻咽喉科杂志》2015年第5期372-375,共4页Chinese Journal of Otorhinolaryngology in Integrative Medicine

摘　　要：目的研究体位性睡眠呼吸暂停(PSA)在阻塞性睡眠呼吸暂停综合征(OSAS)患者中发生率及临床特征。方法收集我院睡眠中心诊治的OSAS患者,分别调查其中分型属PSA者数目及总发生率及轻度、中度、重度OSAS患者中PSA的例数和发生率。挑选OSAS患者平均分层随机化分成呼吸暂停低通气指数(AHI)及性别比例相匹配的PSA组和非PSA组,每组患者41例,分别比较PSA组和非PSA组间患者年龄、腰围、颈围、BMI、OSAS的可能病程及多导睡眠监测(PSG)各指标。结果 575例阻塞性睡眠呼吸暂停综合征患者中体位性睡眠呼吸暂停的患者为104例,总体发生率为18.09%。轻度OSAS中的PSA发生率为38.66%(75/194),中度OSAS的PSA发生率为12.25%(25/204),在重度OSAS的PSA发生率为2.26%(4/177)。组间比较,PSA组的颈围较非PSA组细(36.12±1.90 cm vs 39.83±1.74 cm,P=0.020),PSA组的BMI指数较非PSA组低(24.25±2.80 vs 27.96±2.61,P=0.019),PSA组的0SAS的病程较非PSA组短(3.58±2.80 vs 5.77±2.61,P=0.030)。仰卧位睡眠占总睡眠时间比,PSA组较非PSA组高(90.01%±7.26%vs 78.05%±7.79%,P=0.008),但两组间臀围、腰围、年龄、睡眠期mini SpO_2、mean SpO_2均无显著性差异(P>0.05)。结论 PSA在程度较轻的OSAS患者中发生率较高。同等AHI水平上,PSA患者的颈围较细,BMI较低、睡眠期仰卧位时间比较长、OSAS病程可能较短。Objective To study incidence and some clinical features for positional sleep apnea patients Methods OSAS patients from sleep diagnosis and treatment centers of our hospital were collected. It was investigated the number and incidence of between total OSAS, mild, moderate, and severe OSAS. Patients were stratified and randomly grouped into 2 groups which were apneahypopnea index （AHI） and the sex ratio matched and then PSA group and non-PSA group contained the same number of 41 cases. The patient＇s age, waist circumference, neck circumference, BMI, course of OSAS and the parameters of polysomnography （PSG） of PSA non-PSA group were compared. Results There were 104 cases of PSA in 575 cases of obstructive sleep apnea syndrome, with the overall incidence rate of 18.09%, mild PSA incidence in OSAS of 38.66% （75/194）, moderate PSA incidence in OSAS of 12.25% （25/204）, severe PSA incidence in OSAS of 2.26%（4/177）. Between two groups, it was that waist circumference of PSA group was smaller than that of the non-PSA group （36.12±1.90cm vs 39.83±1.74cm, P= 0.020）, BMI index of PSA group was smaller than that of the non-PSA group （24.25±2.80 vs 27.96±2.61, P= 0.019）, the course OSAS of PSA group was shorter than that of the non-PSA group （3.58±2.80 vs 5.77±2.61, P = 0.030）, Supine sleep time in the total sleep time of PSA group was longer than that of the non- PSA group （90.01%±7.26% vs 78.05%±7.79%, P= 0.008）, but there were no significant differences of hips, waist circumference, age, sleep miniSpO2, meanSpO2 in comparison between two groups （P〉0.05. Conclusion There were high incidence of PSA among mild OSAS patients compared with other OSAS patients, carried smaller neck circumference, lower BMI, shorter the course OSAS and longer supine sleep time in the total sleep time,

关 键 词：阻塞性睡眠呼吸暂停 体位性睡眠呼吸暂停 多导睡眠监测 

分 类 号：R766[医药卫生—耳鼻咽喉科]