Q开关1064 nm激光联合微针导入治疗黄褐斑的临床效果  

Efficacy of Q-switch 1064 nm laser combined with microneedle technology for treatment of melasma

作　　者：王敏[1] 晏洪波[1] 杨凌云[1] 李其爱[1] 龚雪[1] 

机构地区：[1]广州军区武汉总医院皮肤科,430070,

出　　处：《中华医学美学美容杂志》2015年第6期347-349,共3页Chinese Journal of Medical Aesthetics and Cosmetology

摘　　要：目的 探讨Q开关1064 nm激光联合微针导入治疗黄褐斑的临床疗效.方法 将黄褐斑患者70例,按治疗方法不同分为3组：联合治疗组28例,采用Q开关1064 nm激光和微针导入联合治疗,间隔2-3周,两项治疗交替进行,疗程持续2-6个月;单用微针导入治疗组20例;单用Q开关1064 nm激光治疗组22例.观察3组的治疗效果及不良反应,对色斑消褪面积进行测评.结果 70例患者中,多数患者每次治疗后黄褐斑的面积、色泽深度均有明显好转,联合治疗组有效率为78.6％（22/28）,单用微针导入治疗组有效率为40.0％（8/20）,单用Q开关1064 nm激光治疗组有效率为45.4％（10/22）,联合治疗组优于单用Q开关1064 nm激光治疗组或单用微针导入治疗组,总有效率比较,差异均有统计学意义（P＜0.05）.结论 Q开关1064 nm激光联合微针导入治疗黄褐斑安全有效,具有明显的优势,操作易于掌握,值得临床广泛推广.Objective To investigate the clinical efficacy of Q-switch 1064 nm wavelength laser combining with microneedle technology for the treatment of melasma.Methods 70 melasma patients were selected in the Out-patient Department of Wuhan General Hospital of Guangzhou Military Command from July 2012 to Sept.2013.The patients were randomly divided into 3 groups：the combining therapy group （patients in this group received Q-switch 1064 nm wavelength laser combining with microneedles technology,the treatment interval was 2 or 3 weeks,and the whole course was 2-6 months）;the microneedle group and the Q-switch 1064 nm wavelength laser group.The effect and the adverse reaction were observed and recorded during the treatment,and the reduced area of the pigment patch was also measured to judge the total efficacy after the course.Results The total effective rate was 78.6% （22/28） in the combining therapy group and 40.0% （8/20） in the microneedle group,45.5% （10/22） in the Q-switch 1064 nm wavelength laser group.There were statistically significant differences between the combining therapy group and the other groups （P1 〈0.05,P2 〈0.05）,without obvious adverse reaction.Conclusions It is significantly better to use American Medlite C6 Q-switch 1064 nm wavelength laser combining with microneedles technology than that of the single use of Q-switch 1064 nm wavelength laser or microneedles in the treatment for the patients with melasma.The method is also simple to handle and suitable for clinical application.

关 键 词：黄褐斑 Q开关激光 微针 

分 类 号：R758.42[医药卫生—皮肤病学与性病学]