血清唾液酸测定在毛细支气管炎患儿混合感染中的临床意义  

Clinical Analysis of Serum Sialic Acid in Mixed Infection of the Children of Bronchiolitis

作　　者：韩丽平[1] 段全纪[2] 周清霞[2] 

机构地区：[1]潍坊医学院儿科学教研室,山东潍坊261053 [2]潍坊市人民医院儿科

出　　处：《潍坊医学院学报》2015年第6期448-450,共3页Acta Academiae Medicinae Weifang

摘　　要：目的：探讨血清唾液酸在毛细支气管炎患儿中混合感染的应用价值。方法选取2014年6月～2015年7月在潍坊市人民医院住院治疗的100例毛细支气管炎患儿，利用Olympus-2700全自动生化分析仪检测血清唾液酸含量；同时利用间接免疫荧光法检测患儿血清中9项呼吸道病原体。结果血清唾液酸含量占前3位的感染患儿分别为混合感染者（1000．5±49．9）mg／L、其次为肺炎支原体感染者（920．4±97．0）mg／L和副流感病毒感染者（844．7±25．0）mg／L，其中混合感染患儿高于其他患儿，差异有统计学意义（P＜0．05）；100例患儿中有22例为混合感染（22．0％），混合感染患儿中又以混合肺炎支原体多见（86．4％）。结论血清唾液酸水平越高，提示混合感染的可能性越大；肺炎支原体容易混合其它病原体感染。Objective To explore application value of serum sialic acid in mixed infection of bronchiolitis. Methods Serum sialic acid was measured by Olympus-2700 Automatic biochemical analyzer.The IgM antibodies against nine types of respiratory pathogens were detected by Indirect immunofluorescence assay in 100 bronchiolitis infants trea-ted in weifang people＆#39;s hospital from June 2014 to July 2015.Results The serum sialic acid in infants infected mixed pathogens was the most highest[（1000.5 ±49.9）mg/L],followed by Mycoplasma pneumoniae[（920.4 ±97.0）mg/L] and parainfluenza virus[（844.7 ±25.0）mg/L],the first group was higher than other groups,there were statistical sig-nificance in them（P〈0.05）;22 infants had mixed pathogens in 100 infants（22.0%）.Mycoplasma pneumoniae was the most common in 22 infants of mixed infection（86.4%） .Conclusion The higher the serum sialic acid,the more possi-ble the mixed infection;Mycoplasma pneumoniae easily appear in mixed infection.

关 键 词：毛细支气管炎 婴幼儿 血清唾液酸 混合感染 肺炎支原体 

分 类 号：R725.6[医药卫生—儿科]