瑞舒伐他汀钙片治疗原发性高血压的疗效观察  

Rui shu laval statin calcium treatment curative effect observation of primary hypertension

作　　者：王东伟[1] 刘玉清[1] 张娟[1] 张艳霞[1] 买玉兰 秦向豪 

机构地区：[1]郑州大学附属郑州中心医院,河南郑州450007

出　　处：《中西医结合心血管病电子杂志》2015年第16期3-5,共3页Cardiovascular Disease Electronic Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的观察瑞舒伐他汀片治疗原发性高血压的疗效。方法选取我院收治的原发性高血压患者120例,随机分为治疗组和对照组,各60例。对照组给予常规低脂、低盐饮食,口服左旋氨氯地平片5 mg/d治疗,治疗组在对照组的基础上,加服瑞舒伐他汀片,10 mg/d。观察并比较两组患者治疗前后血压和血脂的变化。结果治疗前两组患者的血压和血脂水平比较差异均无统计学意义(P>0.05),治疗后两组患者的收缩压、舒张压均明显降低(P<0.05),治疗组较对照组下降更明显(P<0.05)。治疗后治疗组总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)均明显降低,高密度脂蛋白(HDL)明显升高(P<0.05),对照组上述各项指标均无明显变化(P>0.05),差异均有统计学意义(P<0.05)。结论瑞舒伐他汀具有明显降低血脂和血压的作用,治疗原发性高血压疗效确切,安全可靠。Objective To observe the curative effect of the treatment of essential hypertension with the treatment of the patients with essential hypertension.Methods 120 patients with essential hypertension were randomly divided into treatment group and control group,60 cases in each group,the control group received conventional low fat,low salt diet,5 mg/d treatment,the treatment group on the basis of the control group,plus 10 mg/d.Blood pressure and blood lipid were observed and compared before and after treatment in the two groups.Results There was no significant difference in blood pressure and blood lipid levels between the two groups before treatment（P〉0.05）.The systolic blood pressure and diastolic blood pressure of the two groups were significantly decreased（P〈0.05）.and the treatment group was significantly lower than the control group（P〈0.05）.After treatment, total cholesterol（TC）,triglyceride（TG）,low density lipoprotein（LDL）were significantly decreased, and high density lipoprotein（HDL）was significantly higher（P〈0.05）,and the control group had no significant change（P〉0.05）,the difference was statistically significant（P〈0.05）.Conclusion The effect of the treatment of essential hypertension and the effect of the treatment of essential hypertension is effective,safe and reliable.

关 键 词：瑞舒伐他汀 原发性高血压 高脂血症 疗效 

分 类 号：R544.1[医药卫生—心血管疾病]