2013年天津市乙型肝炎相关肝硬化肝癌死亡减寿年数分析  

Analysis on potential years of life lost caused by hepatitis B related cirrhosis and hepatocarcinoma in Tianjin of the year 2013

作　　者：吴伟慎[1] 李超[1] 赵莹[1] 何海艳[1] 陈静[1] 

机构地区：[1]天津市疾病预防控制中心,300011

出　　处：《职业与健康》2015年第23期3246-3248,共3页Occupation and Health

摘　　要：目的评估天津市乙型肝炎（乙肝）相关肝硬化、肝癌死亡潜在寿命损失。方法按死亡时间对2013年自《人口死亡信息登记管理系统》导出的根本死因中肝硬化、肝癌死亡数据进行排序,通过系统抽样抽取死者名单,通过家属和医院调查确认其死亡根本原因与乙肝病毒（HBV）慢性感染的关联,然后计算乙肝相关死亡潜在寿命损失等。结果抽取的770例死者中经核查后与乙肝相关的有391例,潜在减寿年数（PLYY）6167a,主要发生在40-59岁（4 299 a）,其中肝硬化潜在减寿年数均值（ALYY）（19±12）岁,高于肝癌的（16±11）岁（Z=2.140,P=0.032）。男性PLYY为5002a,ALYY为（18±11）岁,推算减寿率（YPLLR）为1.73‰,分别高于女性的1165a,（14±12）岁（Z=2.315,P=0.021）和0.58‰（χ-2=3906.967,P=0.000）。结论天津中年男性人群乙肝导致的相关肝硬化和肝癌死亡的潜在寿命损失仍较大,应完善死因登记中乙肝等传染病相关死亡登记。[Objective]To evaluate the potential years of life lost（PYLL） caused by hepatitis B related cirrhosis and hepatocarcinoma in Tianjin.[Methods]The data of cirrhosis and hepatocarcinoma death cases in 2013,which were downloaded from the Population death registration management information system,were sorted according to death time,then some records were randomly chosen by systematic sampling,to investigate their families and cured hospitals for conforming the correlation between death and hepatitis B chronic infection,and PYLL related to hepatitis B was calculated.[Results]Totally 391 deaths were related to hepatitis B among 770 investigated deaths,PYLL were 6167 years,and mainly occurred in 40-59 year-old age group.The average years of potential life lost（ALYY） of liver cirrhosis（19＋12 years） was higher than that of hepatocarcinoma（16±11years） significantly（Z=2.140,P=0.032）.The PYLL,ALYY in males（5 002 years,18±11 years） was higher than those in females（1165 years,14±12 years） significantly（Z=2.315,P=0.021）,while years of potential life lost rate（YPLLR） in males（1.73‰） was higher than that in females（0.58‰） significantly（χ-2=3906.967,P=0.000）.[Conclusion]PYLL caused by hepatitis B related cirrhosis and hepatocarcinoma among middle-aged male population is high in Tianjin.Moreover,it is necessary to complete the death records related to infectious disease.

关 键 词：乙型肝炎 死亡 潜在减寿年数 

分 类 号：R181.3[医药卫生—流行病学]