参附注射液治疗感染性休克疗效观察  

Observation of therapeutic effects of shenfu Injection treating patients with septic shock

作　　者：钟恺立[1] 江波[1] 

机构地区：[1]成都市第一人民医院ICU四川,成都610041

出　　处：《医药前沿》2015年第33期81-82,共2页Journal of Frontiers of Medicine

摘　　要：目的：观察参附注射液治疗感染性休克的临床疗效.方法：64例感染性休克患者随机分为两组,对照组采用西医常规治疗,治疗组在常规治疗基础上加用参附注射液.结果：治疗组平均动脉压（MAP）达标时间短、达标时去甲肾上腺素使用量小,均优于对照组（P〈0.05）;治疗24h后MAP、中心静脉血氧饱和度（SCVO2）、乳酸水平、尿量指标比较,治疗组优于对照组（P〈0.05）;治疗组住ICU时间短于对照组（P〈0.05）;两组死亡率无差异（P〉0.05）.结论：在指南推荐的标准治疗基础上加用参附注射液,能迅速提升感染性休克患者血压,改善重要指标,缩短住ICU时间,但不能改善生存率.Objective To observe the effect of shenfu Injection in patients with septic shock.Methods 64 patients with septic shock were divided into two groups randomly, the control group received conventional treatment and the treatment group received conventional treatment plus shenfu Injection.Results In the treatment group, compliance time of the mean arterial pressure（MAP） and the norepinephrine amount were better than those of the control group（P〈0.05）; After treatment for 24h, these indicators of the treatment group were better than those of the control group including MAP, the central venous oxygen saturation（SCVO2）, the lactate levels and the urine volume（P〈0.05）; Compared with the control group the ICU stay below in the treatment group（P〈0.05）; no statistically significant difference in mortality rate was showed between the two groups（P〉0.05）.Conclusion Use of Shenfu Injection can improve the arterial pressure and important indicators , shorten ICU stay of patients with Septic shock, but it can not improve the survival rate.

关 键 词：参附注射液 感染性休克 中西医结合疗法 

分 类 号：R453[医药卫生—治疗学]