血清维生素D含量与产褥感染的关系  

Relationship between serum vitamin D level and puerperal infection

作　　者：黄剑青[1] 彭思苹 张兵[1] 陈惠霞[1] 叶敏仪[1] 

机构地区：[1]广东省佛山市南海区第六人民医院产科,广东佛山528248

出　　处：《中国医药导报》2015年第36期89-91,96,共4页China Medical Herald

基　　金：广东省佛山市医学类科技攻关项目(20111021020027)

摘　　要：目的探讨孕晚期女性血清中25-（OH）D，含量高低与产褥病的相关性。方法选择2012年6月。2013年6月于广东省佛山市南海区第六人民医院住院分娩的208例正常孕晚期妇女作为研究对象，检测其血清中25-（OH）D，的浓度水平，并以50nmol／L：勾标准，将所有孕妇分为高维生素D组（≥50nmol／L为高维生素D组）和低维生素D组（〈50nmol／L为低维生素组）。分别计算两组孕妇的产褥感染率和产褥病率，结合其一般资料统计分析血清维生素D含量与产褥感染、产褥病之间的相关性。所得数据采用统计学软件SPSS20．0进行建模分析。结果208例孕晚期妇女血清中25-（OH）D，的平均含量为（70．15±14．52）nmol／L，纳入高维生素D组和低维生素D组分别为102例和106例，两组孕妇年龄、分娩方式、孕产史和手术操作情况比较，差异均无统计学意义（P〉0．05），但高维生素D组的产褥感染率（0．98％）和产褥病率（1．96％）均显著低于低维生素D组（6．61％、14．2％），差异均有统计学意义（P〈0．05）。结论高维生素D水平对孕妇分娩时和产后预防产褥病，特别是产褥感染均有着关键作用，临床用药方案上应针对低维生素水平的孕妇定期及时补充维生素D。Objective To study the relationship between the content of serum 25-（OH）D3 in the late pregnant women and puerperalism. Methods 208 normal late pregnant primipara who given birth in the Sixth People＇s Hospital in Nan- hai District from June 2012 to Jane 2013 were selected. They were divided into high vitamin D group （≥50 nmol/L） and low vitamin D group （〈50 nmol/L） according to the concentration of serum 25-（OH）D3 levels used 50 nmol/L as a standard. The rate of puerperal infeetion and puerperal morbidity of two groups were calculated and the relationship between the content of serum vitamin D and puerperal infection, puerperalism was statistically analyzed based on the general data. All the data was trodeled and analyzed by statistieal software SPSS 20.0. Results The average content of serum 25-（OH）D3 in 208 late pregnant women was （70.15±14.52） nmol/L, 102 cases and 106 cases were brought into high vitamin D group and low vitamin D group respectively. Age, delivery mode, maternal history and operative procedure in two groups had no statistically significant differences （P 〉 0.05）. The rate of puerperal infection （0.98%） and puerperal morbidity （1.96%） of high vitamin D group were significantly lower than those of low vitamin D group （6.61%, 14.2%）, the differences of two were statistically significant （P 〈 0.05）. Conclusion The level of high vitamin D plays a key role in preventing puerperalism especially puerperal infection at the time of birth and after delivery. The pregnant women of low vitamin D level should be supplied with vitamin D regularly and timely in therapcutic schemes.

关 键 词：维生素D 产褥感染 产褥病 相关性 

分 类 号：R714.62[医药卫生—妇产科学]