实时动态血糖监测联合胰岛素泵治疗糖尿病肾病腹膜透析患者血糖的临床观察  

Clinical study of the accuracy of real-time continuous monitoring system combined with continuous subcutaneous insulin in treatment of diabetic nephropathy patients with peritoneal dialysis

作　　者：杨光[1] 黎小燕[2] 罗亮[1] 钟树妹[2] 张秋平[2] 

机构地区：[1]江西省赣州市人民医院肾脏内科,江西赣州341000 [2]江西省赣州市人民医院内分泌科,江西赣州341000

出　　处：《中国当代医药》2015年第35期43-45,共3页China Modern Medicine

基　　金：江西省赣州市指导性科技计划(GZ2014ZSF217)

摘　　要：目的观察实时动态血糖监测系统（CGMS）联合胰岛素泵治疗（＂3C＂疗法）对糖尿病肾病腹膜透析患者血糖控制的临床疗效。方法将2013年5月-2015年5月在赣州市人民医院腹膜透析中心行腹膜透析的30例糖尿病终末期肾病患者随机分为3C组和对照组,3C组14例采用＂3C＂疗法,对照组16例采用CGMS联合多次皮下胰岛素注射治疗。观察两组患者血糖达标时间,血糖达标时日胰岛素使用总量,高、低血糖事件。结果 3C组血糖达标时间短于对照组,血糖达标时日胰岛素使用总量少于对照组,3C组高、低血糖发生率均低于对照组,差异有统计学意义（P〈0.05）。结论在糖尿病肾病腹膜透析患者降糖方案中,＂3C＂疗法优于CGMS联合多次皮下胰岛素注射治疗。Objective To investigate the clinical effect of the accuracy of real-time dynamic continuous glucose monitoring system（CGMS） combined with continuous subcutaneous insulin（3C） in the treatment of diabetic nephropathy patients with peritoneal dialysis. Methods 30 patients with diabetic nephropathy in end-stage were divided into 3C group and control group.3C group（n=14） received ＂3C＂ treatment and control group（n=16） were treated by CGMS combined with multiple subcutaneous insulin injection.The time to achieve the target,insulin dose,hyperglycemia and hypoglycemia were measured and compared between two groups. Results Compared with control group,the time to achieve the target was shorter and the insulin dose was lower in 3C group.The incidence of hyperglycemia and hypoglycemia in 3C group was lower than that in control group,with statistical difference（P〈0.05）. Conclusion ＂3C＂ therapy is superior to CGMS combined multiple subcutaneous insulin in the treatment of diabetic nephropathy patients with peritoneal dialysis.

关 键 词：糖尿病肾病 腹膜透析 “3C”疗法 实时动态血糖监测系统 胰岛素泵 

分 类 号：R587.1[医药卫生—内分泌]