布地奈德吸入治疗小儿急性感染性喉炎的临床研究  

Clinical study of inhaling budesonide in the treatment of children with acute infectious laryngitis

作　　者：汪培勤 马莹莹[1] 罗建军[1] 

机构地区：[1]深圳市龙岗区妇幼保健院小儿内科,深圳518172

出　　处：《中国当代医药》2015年第35期88-89,93,共3页China Modern Medicine

摘　　要：目的探讨布地奈德混悬液吸入治疗小儿急性感染性喉炎的疗效及安全性。方法选取本院2012年1月-2015年1月收治的200例急性感染性喉炎患儿作为研究对象,根据治疗方法不同分为观察组与对照组,各100例。对照组采用常规综合治疗方案,观察组在对照组的基础上给予布地奈德混悬液空气压缩泵超声雾化吸入治疗,比较两组的临床治疗效果。结果观察组的总有效率为96.0%,显著高于对照组的77.0%,差异有统计学意义（P〈0.05）。观察组的声音嘶哑消失时间、吸气性喉鸣消失时间、犬吠样咳嗽消失时间显著短于对照组,差异有统计学意义（P〈0.05）。两组治疗期间均未发现不良反应。结论布地奈德混悬液超声雾化吸入治疗小儿急性感染性喉炎效果显著,值得临床推广应用。Objective To explore the efficacy and safety of inhaling budesonide in the treatment of children with acute infectious laryngitis. Methods 200 pediatric patients with acute infectious laryngitis from January 2012 to January 2015 in our hospital were selected and divided into the observation group and the control group according to different therapeutic methods,100 cases in each group.The control group was treated with conventional comprehensive therapeutic regimen,the observation group was treated with budesonide suspension inhaling by ultrasonic atomization via air compression pump on the basis of the control group.The clinical therapeutic efficacy in two groups was compared. Results The total effective rate in the observation group was 96.0%,whgich was higher than 77.0% in the control group,with significant difference（P〈0.05）.Disappearing time of hoarseness,inspiratory stridor and barking cough in the observation group was shorter than that in the control group,with significant difference（P〈0.05）.There was no adverse reaction occurred in two groups during treatment. Conclusion Ultrasonic atomization inhalation of budesonide suspension can obtain a remarkable effect in the treatment of children with acute infectious laryngitis,it is worthy of clinical promotion and application.

关 键 词：布地奈德 空气压缩泵超声雾化 吸入治疗 急性感染性喉炎 

分 类 号：R725.6[医药卫生—儿科]