玛咖酰胺研究进展  

Research progress on macamides

作　　者：陈金金[1,2] 赵兵[1] 

机构地区：[1]中国科学院过程工程研究所生化工程国家重点实验室,北京100190 [2]中国科学院大学,北京100049

出　　处：《中草药》2015年第21期3284-3288,共5页Chinese Traditional and Herbal Drugs

基　　金：国家"863"项目(2012AA021702-4)

摘　　要：玛咖因其丰富的营养价值和多样的药用价值被作为食品和传统药材长期食用。玛咖酰胺为其特征性化合物,是一系列非极性长链脂肪酸的氮苄基酰胺类化合物,具有神经保护及神经系统调节等活性。综述了玛咖酰胺的种类,及其化学合成、检测方法、生物活性的国内外研究进展,为进一步研究及开发利用提供参考。Maca（Lepidium meyenii Walp.） has been used as both food and traditional medicine for centuries for its high nutritional value and multi-medicinal properties. Macamides, the marker compounds of maca, are a series of nonpolar, long chain fatty acid N-benzylamides. Most of them have neuroprotective and neuroregulation effects. In this paper, we reviewed the structures of macamides, methods of chemical synthesis, and quantitative determination, and their bioactivities to provide a reference for further research and development.

关 键 词：玛咖 玛咖酰胺 药材 神经保护 化学合成 

分 类 号：R931.6[医药卫生—生药学]