桂皮醛药理作用的研究进展  

Research progress of trans-cinnamaldehyde pharmacological effects

作　　者：张利青[1] 张占刚[1] 付岩[1] 徐颖[1] 

机构地区：[1]上海中医药大学生理教研室,上海201203

出　　处：《中国中药杂志》2015年第23期4568-4572,共5页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(81274119);上海市教育委员会科研创新项目(13YZ050);上海市教育委员会重点学科项目(J50301)

摘　　要：桂皮醛是中国传统中药材桂枝或肉桂挥发油的主要成分,为烯醛类有机化合物,具有抗炎、解热镇痛、抗肿瘤、抗菌、降糖、抗肥胖和神经保护等多种药理作用。对神经系统、心血管、肿瘤、糖尿病等疾病均有一定的防治作用,作为预防保健的天然药物具有较好临床和市场潜力。该文对近5年来国内外关于桂皮醛的药理作用及其机制研究进行了综述,以期对桂皮醛的深入研究和开发提供一定的科学依据。Trans-cinnamaldehyde,the main component of volatile oil from cassia twig or Cinnamomum cassia,which is a traditional Chinese herbal medicine. Trans-cinnamaldehyde is a kind olefine aldehyde of organic compounds and has many pharmacological properties,such as anti-inflammatory,anti-tumor,anti-bacterial,antidiabetic,anti-obesity,and neuroprotection etc. The compound has preventive and therapeutic effects on the nervous system,cardiovascular,cancer,diabetes and other diseases. Trans-cinnamaldehyde,as a preventive care of nature medicine,has great clinical and market potential. This paper gives a review about the pharmacological effects and mechanism of trans-cinnamaldehyde researched in the latest five years. We hope to provide some basic information for further research on trans-cinnamaldehyde.

关 键 词：桂皮醛 药理作用 研究进展 

分 类 号：R285[医药卫生—中药学]