库欣综合征所致高凝状态的研究进展  

Research progress on hypercoagulable state in Cushing's syndrome

作　　者：吴遐[1] 高路[1] 幸兵[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院神经外科,北京100730

出　　处：《基础医学与临床》2016年第1期121-124,共4页Basic and Clinical Medicine

基　　金：首都临床特色应用研究(Z151100004015099)

摘　　要：库欣综合征是高皮质醇血症所致的临床症候群,该病患者常合并高凝状态,其动静脉血栓事件、心血管病发生率乃至病死率均高于普通人群。本文将介绍库欣综合征高凝状态的病理生理机制,并对临床上预防性使用抗凝药物提供指导。Cushing＇s syndrome（ CS） results from chronic exposure to excessive levels of glucocorticoids. Generally it is accompanied by a hypercoagulable state. Patients with CS have a higher risk of arterial and venous thrombotic events,cardiovascular disease morbidity and mortality. This review aims to introduce its pathophysiological mechanisms,and to provide examples and guidelines for antithrombotic prophylaxis in CS.

关 键 词：库欣综合征 高凝状态 静脉血栓栓塞症 

分 类 号：R586.2[医药卫生—内分泌]