系统性硬化病患者高分辨率胃肠动力分析1例  

High resolution gastrointestinal monitoring in a systemic sclerosis patient with gastrointestinal dysfunction

作　　者：宿慧[1] 姜国俊[1] 刘揆亮[1] 孟明明[1] 刘红[1] 吴静[1] 

机构地区：[1]首都医科大学附属北京世纪坛医院消化内科,北京市100038

出　　处：《世界华人消化杂志》2015年第35期5739-5742,共4页World Chinese Journal of Digestology

摘　　要：系统性硬化病患者胃肠道受累很常见.本文对1例有胃肠道受累表现的系统性硬化病患者进行高分辨率胃肠动力检查.食管测显示食管体部无蠕动,食管下括约肌(low esophageal sphincter,LES)压力减低;24 h p H值-阻抗监测符合重度胃食管反流;肛门直肠测压显示肛门括约肌压力带偏短且不能持续收缩,直肠感知功能减退.高分辨率胃肠动力检查能直观的显示系统性硬化病患者食管及肛门直肠功能受累.Gastrointestinal dysfunction is commonin systemic sclerosis patients, but the characteristic findings of high resolution gastrointestinal monitoring and 24-h pH-Z monitoring in these patients are rarely reported. We performed high resolution esophageal pressure monitoring, 24-hour esophageal pH-Z monitoring, and high resolution anorectal pressure monitoring （3D） in a systemic sclerosis patient with gastrointestinal dysfunction. Esophageal pressure monitoring showed that the distal peristaltic pressure wave was absent, the lower esophageal sphincter （LES） relaxed, and the bolus could not be cleared from the esophagus. 24-h esophageal pH-Z monitoring showed severe gastroesophageal reflux, obvious weak acid reflux, and symptoms associated with acid reflux. Anorectal pressure monitoring showed that the pressure band of resting anal sphincter was narrow, and the initial feeling of defecation and maximum tolerance amount were significantly weaken. Thus, high resolution gastrointestinal monitoring allows to monitor gastrointestinal dysfunction in systemic sclerosis patients.

关 键 词：系统性硬化 胃肠动力 高分辨率测压 

分 类 号：R593.2[医药卫生—内科学]