分层二维斑点追踪显像技术评价糖尿病患者左室心肌各层收缩功能的变化  

Evaluation of left ventricular strain in diabetic patients using layer-specific two-dimensional speckle trackingimaging

作　　者：薛衍敏 潘翠珍[1] 李政[1] 史静[1] 舒先红[1] 

机构地区：[1]复旦大学附属中山医院心超室上海市心血管病研究所上海市影像医学研究所,上海200032

出　　处：《中华超声影像学杂志》2015年第12期1024-1027,共4页Chinese Journal of Ultrasonography

基　　金：基金项目：上海市科委基金项目（14411962500）;上海市科委医学引导项目（124119a7702）;国家自然基金面上项目（81371576）

摘　　要：目的通过分层二维斑点追踪显像技术评价糖尿病患者心肌分层应变的变化趋势。方法对57例糖尿病患者和6（）例正常对照者，应用GEVividE9和EchoPac工作站的分层二维斑点追踪技术，比较左室内膜下、中层、外膜下心肌的纵向和环向应变参数。结果糖尿病组内膜下、中层、外膜下心肌的纵向应变均低于正常对照组（P〈0．05）。内膜下心肌和中层的环向应变低于正常对照组（P〈0．05），外膜下心肌环向应变差异无统计学意义。糖尿病组的纵向应变和环向应变均以心内膜下心肌最高，心外膜下心肌最低。结论糖尿病患者左室心肌内膜下、中层、外膜下三层心肌的收缩功能减低，分层二维斑点追踪技术能够敏感发现其心肌收缩功能变化。Objective To quantitatively evaluate the difference in global longitudinal strain（GLS） and global circumferential strain（GCS） of three-layers of cardium between diabetes mellitus （DM） patients using layer-specific speckle-tracking imaging. Methods Fifty-seven DM patients and sixty matched controls were enrolled in the study. GLS and GCS of three-layer cardium were assessed using layer-specific speckle- tracking imaging,available by GE Vivid E9 and EchoPac workstation. Results GLS of three-layer cardium in DM patients were significantly lower than those in normal controls （all P 〈0.05）. GCS of endo- and mid- cardium were significantly lower in DM patients than in normal controls （P〈 0.05）. There was no statistical difference of GCS of epi-cardium between the two groups （P 〉 0.05）. GLS and GCS of three- layer cardium was highest in endo-cardium and lowest in epi-cardium. Conclusions GLS of three layer cardiurn may be a sensitive indicator of early left ventricular systolic dysfunction in DM patients with normal ejection fraction.

关 键 词：超声心动描记术 糖尿病 心室功能 左 应变 分层斑点追踪显像 

分 类 号：R445.1[医药卫生—影像医学与核医学] R587.1[医药卫生—诊断学]