1例脊髓灰质炎减毒活疫苗相关麻痹型病例的报告  

作　　者：张肖肖[1] 王长双[1] 肖占沛[1] 王燕[1] 路明霞[1] 马雅婷[1] 张延炀[1] 

机构地区：[1]河南省疾病预防控制中心免疫规划所,河南450016

出　　处：《当代医学》2016年第1期24-25,共2页Contemporary Medicine

基　　金：河南省疾病预防控制中心科研基金资助项目;河南省2013年卫生政策研究课题(YWZY 201306)

摘　　要：目的了解脊髓灰质炎活疫苗相关麻痹型病例的发病特征。方法对1例相关麻痹型病例的临床和流行病学资料进行分析。结果病例首次服脊髓灰质炎减毒活疫苗21天后出现双下肢麻痹,病例患肛周脓肿,便标本分离出脊灰疫苗株病毒,麻痹60天后随访有残留麻痹。结论建议将肛周脓肿作为脊髓灰质炎减毒活疫苗接种的禁忌证。Objective To analyze the situation of vaccine associated paralytic poliomyelitis（VAPP）. Methods The individual characteristics of VAPP were analyzed descriptively. Results The case with crissum abscess appeared paralysis with limb after 21 days since the first time recipients, vaccine strains were isolated from the VAPP case, the case was maintained with residual paralysis by follow-up. Conclusion Crissum abscess is recommended as a contraindication for oral poliovirus vaccine.

关 键 词：口服脊髓灰质炎减毒活疫苗 疫苗相关病例 特征 

分 类 号：R186[医药卫生—流行病学]