普通变异性免疫缺陷病合并麦胶性肠病一例并文献复习  

Common Variable Immune Deficiency Combined with Celiac Disease: A Case Report and Literatures Review

作　　者：张娟[1] 杨小东[1] 王玉芳[1] 胡秋芳[1] 张艺[1] 吴立雪[1] 

机构地区：[1]四川大学华西医院呼吸内科,成都610041

出　　处：《华西医学》2015年第12期2208-2211,共4页West China Medical Journal

摘　　要：目的观察普通变异性免疫缺陷病(CVID)合并麦胶性肠病的临床特征并探讨其诊治方法及疗效。方法回顾分析2013年11月收治的1例CVID合并麦胶性肠病患者的诊断及治疗经过,总结其临床特征、诊疗要点、相关治疗及预后评价。结果患者经严格无麦胶饮食,予以输注丙种球蛋白等治疗,腹泻症状明显改善,复查血清免疫球蛋白升高。结论 CVID是一种常见的原发性体液免疫缺陷病,麦胶性肠病以小肠绒毛损害和营养物质吸收障碍为特征,二者关系密切。简单无麦胶饮食可以改善症状,控制病情,提高患者生活质量。Objective To enhance the understanding of common variable immune dei ciency（CVID） combined with celiac disease in order to diagnose and treat the disease as early as possible and delay its complications through the treatment of the disease and study on related literatures. Methods h e experience of diagnosing and treating one case of CVID combined with celiac disease in November 2013 was reported in the present study, and the related literatures were reviewed. Results At er strict gluten-free diet and infusion of intravenous immune globulin, the patient＇s diarrhea relieved and serum immunoglobulin elevated. Conclusions CVID is the most frequent symptomatic primary immune deficiency which is related to celiac disease closely, a gluten-sensitive condition characterized by a variable degree of villous atrophy. Once diagnosed, gluten-free diet can alleviate the symptoms.

关 键 词：普通变异性免疫缺陷病 麦胶性肠病 血清免疫球蛋白降低 无麦胶饮食 文献复习 

分 类 号：R593.2[医药卫生—内科学]