59种涉水产品遗传毒性分析  

作　　者：张少平[1] 孔建[1] 治洪[1] 张明[1] 李毅民[1] 

机构地区：[1]中国疾病预防控制中心环境与健康相关产品安全所,北京100021

出　　处：《中国卫生监督杂志》2015年第6期565-567,共3页Chinese Journal of Health Inspection

摘　　要：目的对59种受检涉水产品的遗传毒性进行判断分析。方法利用小鼠骨髓嗜多染红细胞微核试验和鼠伤寒沙门氏菌/回复突变试验对59种涉水产品遗传毒性进行测试,并对其遗传毒性特点进行分析。结果 59种受试涉水产品小鼠骨髓嗜多染红细胞微核试验和鼠伤寒沙门氏菌/回复突变试验结果显示均为阴性。结论根据本研究结果,上述59种涉水产品遗传毒性具有相对安全性,但鉴于遗传毒性终点复杂多样,为确认其遗传毒性特点,尚需进一步结合其他测试结果进行综合判断。Objective To analyse the genotoxicity of 59 products related to water. Methods Mouse bone marrow erythrocyte micronucleus test and Salmonella typhimurium/reverse mutation assay（Ames） were used to test for the genotoxicity of 59 products related to water. Results The toxicological results of all types of product related to water were nega- tive. Conclusion 59 tested products related to water showed relatively genetic safety according to our test. Whereas geno- toxicity has diversified toxic phenotype, more experimental study is necessary to identify their genotoxicity.

关 键 词：涉水产品 遗传毒性 安全性 

分 类 号：R123[医药卫生—环境卫生学]