基于中医传承辅助平台探析中风后遗症方剂组方规律  

Analysis on Composition Principles of Prescriptions for Sequela of Apoplexy by Traditional Chinese Medicine Inheritance Platform

作　　者：刘晓枫[1] 刘广玉[1] 王海瑞[2] 毕春玉[2] 于华芸[2] 

机构地区：[1]济南市第五人民医院,济南250022 [2]山东中医药大学基础医学院,济南250355

出　　处：《世界科学技术-中医药现代化》2015年第10期2156-2161,共6页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：高等学校博士学科点专项科研基金(20113731120001):从VEGF信号通路研究加味黄芪当归汤组分配伍对缺血性脑损伤的保护作用;负责人:于华芸;山东省高等学校科技计划项目(J11LF08):加味黄芪当归汤有效组分配伍对局灶性脑缺血大鼠神经保护作用研究;负责人:于华芸

摘　　要：目的:分析中国期刊全文数据库(CNKI)收录的治疗中风后遗症方剂的组方用药规律,为临床治疗中风后遗症提供参考。方法:筛选CNKI收录治疗中风后遗症的方剂,基于中医传承辅助平台,采用软件集成的数据挖掘方法分析处方用药规律。结果:筛选治疗中风后遗症方剂190首,涉及204味中药,活血、益气中药出现频次较高;常用药对36个,频次最高的药对为当归、黄芪,3味中药组合为地龙、当归、黄芪,4味中药组合为川芎、地龙、当归和黄芪。关联分析结果显示,在治疗中风后遗症方剂中,川芎、当归、桃仁、红花、黄芪常配伍应用;演化核心组合48个,新处方11首。结论:中风后遗症的临床治疗重在益气活血通络,标本并治。按药物的性味归经理论选方用药,以药性温热、味甘辛,归肝、脾经者为多。This study was aimed to analyze the composition principles of prescriptions for sequela of apoplexy collected in the CNKI by the Traditional Chinese Medicine Inheritance Platform（TCMIP）, in order to provide a reference for clinical selection of medication. Prescriptions for the sequela of apoplexy treatment in CNKI were collected. Based on the TCMIP, the medication rules of prescription were analyzed by data mining method after data entry. A total of 190 prescriptions involving 204 herbs for sequela of apoplexy treatment were screened and studied. The herbs for blood-activating and qi-tonifying were used with higher frequency. There were 36 commonly used herbal pairs. The herb pair of Dang-Gui（Radix Angelicae Sinensis） and Huang-Qi（Radix Astragali） was with the highest frequency. The herbal combination with three types of herbs was Di-Long（Pheretima）, Dang-Gui and Huang-Qi. The herbal combination with four types of herbs was Chuan-Xiong（Rhizoma Chuanxiong）, DiLong, Dang-Gui and Huang-Qi. The analysis on association rule showed that Chuan-Xiong, Dang-Gui, TaoRen（Semen Persicae）, Hong-Hua（Flos carthami） and Huang-Qi were often combined with each other. A total of 48 core combinations and 11 new prescriptions were mined. It was concluded that the prescriptions for sequela of apoplexy were mainly composed with herbs for blood-activating, qi-tonifying and collateral-dredging. According to the flavor and meridian tropism theory of Chinese medicine, the herbal medication selection in the prescription was mostly warm and hot in nature, sweet and pungent flavor, and the meridian tropism of the liver and spleen meridian.

关 键 词：中风后遗症 中医传承辅助平台 组方规律 文献分析 

分 类 号：R277.7[医药卫生—中医学]