桉属植物中间苯三酚衍生物的研究进展  

Research advances on phloroglucinol derivatives in plants of Eucalyptus L'Héritier

作　　者：李伟[1] 

机构地区：[1]宜春学院化学与生物工程学院,江西省天然活性成分重点实验室,江西宜春336000

出　　处：《中草药》2015年第23期3592-3604,共13页Chinese Traditional and Herbal Drugs

基　　金：江西省科技厅青年科学基金(20142BAB215023);江西省教育厅项目(赣教技字[12698])

摘　　要：桉属为桃金娘科的一个主要属,桉属植物常统称为桉树,其木材、叶、花、果实等是化学工业、香料、医药领域的重要原料。长期以来,桉属植物作为民间药被使用,主要用于治疗流行性感冒、痢疾、湿疹、跌打损伤等。间苯三酚衍生物为桉属植物中最主要的一类化合物,因为其良好的抗菌、抗病毒、抗肿瘤等生物活性,对其研究较为深入。间苯三酚衍生物的结构比较特殊,常与单萜、倍半萜及二萜结合形成杂合物,结构较为复杂、多变,形成的杂合物为桉属植物中一类特有的化合物。目前,从桉属植物中分离得到96个间苯三酚衍生物。通过查阅相关的文献,对其研究概况进行综述。The plants from Eucalyptus L＇Héritier, a main genus of Myrtaceae family, are commonly called as eucalyptus tree, the woods, leaves, flowers, and fruits of which are a kind of important raw materials for chemical industry, medicine, and spices. For a long time, the species in Eucalyptus L＇Héritier are commonly used as folk medicine to treat influenza, dysentery, eczema, and injuries. The mainly bioactive chemical constituents in the species of Eucalyptus L＇Héritier are phloroglucinol derivatives, which are unique to the species in Eucalyptus L＇Héritier. Many phloroglucinol derivatives exhibit the interesting pharmacological activities, such as antimicrobial, antiviral, antitumor effects, and so on. The phloroglucinol derivatives include simple, dimeric, and complex phloroglucinol derivatives originating from mixed biogenesis involving the terpene pathways. By now, 96 phloroglucinol derivatives have been isolated from the plants of Eucalyptus L＇Héritier. Advance in study on their chemical constituents with the biological activities are summarized.

关 键 词：桉属 间苯三酚衍生物 甲酰基间苯三酚化合物 抗菌 抗癌 

分 类 号：R282.71[医药卫生—中药学]