应用CTA对无症状非糖尿病高危人群冠状动脉粥样硬化的研究  

A study of computed tomography angiography( CTA) on coronary atherosclerosis in risk factors asymptomatic population

作　　者：刘烨[1] 王耀彬[1] 陈天金[1] 温友信 韩向东[1] 陈艳琼[1] 杨立[2] 

机构地区：[1]武警北京总队第二医院放射科,100037 [2]解放军总医院放射科,北京100853

出　　处：《武警医学》2015年第12期1237-1240,共4页Medical Journal of the Chinese People's Armed Police Force

摘　　要：目的应用冠状动脉CT血管成像技术（computed tomography angiography,CTA）确定有高危因素,且非糖尿病无冠心病症状者冠状动脉粥样硬化（coronary atherosclerotic,CA）发生率,评价其与高危因素的相关性。方法在非糖尿病无冠心病症状健康查体的人群中,收集有高危因素（性别、年龄、高血压、高脂血症）者并将其分为单项高危因素组、2项及以上高危因素组。统计有高危因素者冠状动脉粥样硬化发生率。结果单因素分析发现,年龄和性别对CA的发生率有统计学差异（χ2=4.6,P=0.0032,χ2=6.5,P=0.0108）。高危因素logistic回归分析得出,年龄与CA的发生率有相关性（OR=1.77,CI=1.19--2.66）。高危因素组间比较,多项高危因素CA的发生率有统计学差异（χ2=4.44,P=0.035）。结论在非糖尿病无症状人群中,CTA能够在一次扫描提供冠状动脉斑块的重要信息,性别、年龄可能对发生CA病变带来更大的风险,作为一项无创性的检查,CTA在CA的诊断中发挥重要作用。Objective To make use of coronary CTA to determine the incidence rate of coronary atherosclerosis for non-diabetic asymptomatic people who have risk factors and evaluate its correlation with risk factors. Methods We recruited non-diabetic asymptomatic people who had high-risk factors（ sex,age,hypertension,hyperlipidaemia） and divided them into single high-risk factor group and multiple high-risk factors group. Statistics was conducted on the incidence rate of disease for people who had high-risk factors in coronary atherosclerosis. Results Single risk factor grouping analysis showed that gender and age had significant difference in the incidence of CA（ χ~2= 4. 6,P = 0. 0032,χ~2= 6. 5,P = 0. 0108）. For risk factors between groups,the incidence of multiple risk factors CA had significant difference（ χ~2= 4. 6,P = 0. 0032,χ~2= 6. 5,P = 0. 0108）. Logistic regression analysis showed that risk factors correlated with age and incidence of CA（ OR = 1. 77,CI = 1. 19- 2. 66）. Conclusions In asymptomatic non-diabetic population,CTA provides important information about coronary plaque in one scan,gender and age may have a greater risk of CA disease. As a non-invasive examination,CTA plays an important role in the diagnosis of CA.

关 键 词：冠状动脉粥样硬化 CT血管成像 危险因素 

分 类 号：R543[医药卫生—心血管疾病]