巢湖地区5028例孕早期妇女TORCH感染回顾性分析  

Retrospective analysis of TORCH infection of 5028 women in the early period of pregnancy in area of Chaohu

作　　者：陶芳[1] 陈博[1] 秦文燕[1] 

机构地区：[1]安徽医科大学附属巢湖医院检验科,安徽巢湖238000

出　　处：《中国优生与遗传杂志》2016年第1期85-86,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的分析巢湖地区孕早期妇女弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒即TORCH的检测结果,探讨其临床意义。方法采用化学发光免疫分析法对5028例孕妇TORCH-Ig M抗体和TORCH-Ig G抗体进行检测分析。结果 HSV-Ig M和HSV-Ig G阳性率最高,差异有统计学意义(P<0.05);因CMV感染导致的不良妊娠发生率为46.94%(23/49),与其他病毒感染导致的不良妊娠相比有统计学意义(P<0.05);不良妊娠结局表现中,流产发生率为67.35%(33/49),与其他不良妊娠结局表现相比,差异有统计学意义。结论巢湖地区孕早期妇女存在一定的TORCH阳性率,TORCH感染是不良妊娠结局的重要危险因素之一,因此在孕早期或孕前进行TORCH检测对指导本地区优生优育工作及提高新生儿人口素质具有重要指导意义。Objective： To analyze TORCH test （namely test of toxoplasmosis, rubella virus, cytomegalovirus and herpes simplex virus） results of women from area of Chaohu in early pregnancy, and to explore its clinical significance. Methods： Detected and analyzed TORCH-IgM and TORCH-IgG antibody in 5028 cases of pregnant women by chemiluminescent immunoassay. Results： The positive rate of HSV-IgM and IgG were of significance in statistics （P〈0.05） . The incidence rate of adverse pregnancy due to CMV infection lead up to 46.94% （23/49） , which was of significance in statistics when compared with adverse pregnancies caused by other virus （P〈0.05） . In different kinds of adverse pregnancy, the incidence rate of abortion was 67.35 （33/49） , which was of significance in statistics when compared with other kinds of adverse pregnancy. Conclusion： There was a clear positive rate of the TORCH test results of women in early pregnancy from Chaohu, and TORCH infection was a significant risk factor for adverse pregnancy, and thus it was quite necessary to have TORCH test in the early stage of pregnancy or before pregnancy, which could make a guidance to the job of prenatal and postnatal care in Chaohu and improve the population quality of newborn.

关 键 词：TORCH感染 不良妊娠 孕早期 优生优育 

分 类 号：R714.251[医药卫生—妇产科学] R446.6[医药卫生—临床医学]