炎性因子诊断感染性疾病的研究进展  

Progress of research on diagnosis of infectious diseases with inflammatory factors

作　　者：黄浩[1] 黄文成[1] 梁艺华[1] 陈晓菊[1] 黄昭东[1] 任宁毅[1] 

机构地区：[1]广西医科大学附属肿瘤医院检验科,广西南宁530021

出　　处：《中华医院感染学杂志》2016年第1期235-237,共3页Chinese Journal of Nosocomiology

基　　金：广西卫生厅基金资助项目(Z2014587)

摘　　要：由于精准治疗所需,抗菌药物使用受到严格控制,感染性疾病诊断指标受到新挑战,以降钙素原(PCT)为代表的新型炎性诊断因子倍受关注;该综述通过分析PCT、C-反应蛋白(CRP)、脂多糖(LPS)诊断感染性疾病的敏感性和特异性,认为PCT、CRP、LPS是诊断感染性疾病较好的诊断指标;提出根据不同的疾病学科(如肿瘤学)甚至病种(如肺炎)建立以之相应的感染诊断cutoff值可能是未来的研究方向。The use of antibiotics is restricted more strictly due to the requirement of accurate treatment.The diagnostic indicators of the infectious diseases face new challenges;the new types of inflammatory diagnostic indications,represented by the procalcitonin（PCT）,were particularly concerned.The review defined the sensitivity and specificity of PCT,C-reactive protein（CRP）,and lipopolysaccharide（LPS）in diagnosis of the infectious diseases and concluded that the PCT,CRP,and LPS were great indicators for diagnosis of the infectious diseases.It would be the future research direction to establish the corresponding cutoff value of diagnosis of infections based on different disciplines（such as oncology）or even diseases（such as pneumonia）.

关 键 词：降钙素原 脂多糖 C-反应蛋白 炎性因子 感染性疾病 

分 类 号：R446[医药卫生—诊断学]