血清胱抑素C在糖尿病肾病诊断中的临床价值  

Diagnostic value of serum cystatin in early diabetic nephropathy

作　　者：刘虹[1] 

机构地区：[1]合肥市第二人民医院检验科,安徽230011

出　　处：《安徽卫生职业技术学院学报》2015年第6期72-73,共2页Journal of Anhui Health Vocational & Technical College

摘　　要：目的:评价血清胱抑素C(Cys C)、血清肌酐(Crea)、尿素氮(URN)在糖尿病肾病(DN)中的诊断价值。方法:59例确诊的DN患者(DN组)、取同期健康体检者50例为对照组(Con组),检测两组血清Cys C和Crea、URN的含量。结果:DN组中的血清Cys C和Crea、URN的含量明显高于Con组(P<0.01);且DN组中血清Cys C的阳性率明显高于血清Crea、URN的阳性率(P<0.05),而血清Crea、URN的阳性率比较无显著性差异(P>0.05)。结论:检测血清Cys C能较早反映DN患者的肾功能损伤。Objective： To study the diagnostic value of serum cystatin C（Cys C）,creatinine（Crea）,and urea nitrogen（URN）in the early diabetic nephropathy（DN）.Methods： The contents of Cys C,Crea and URN urea in 59 cases of DN（DN group） and 50 healthy normal control persons（Con group） were detected. Results：The contents of Cys C,Crea and URN were significantly higher in DN group than those in control group（P0.05）.In DN group,there were significant differences in positive rate among Cys C,Crea and URN（P0.01）,but there were no statistically significant between Crea and URN（P 0.05）.Conclusion： Seurm Cys C detection has important significance in the early diagnosis of DN.

关 键 词：糖尿病肾病 血清胱抑素C 血清肌酐 尿素氮 

分 类 号：R587.2[医药卫生—内分泌]