直肠异常隐窝病灶对糖尿病患者结直肠癌的预警作用研究  

Research on prewarning effect of rectal aberrant crypt foci on colorectal carcinoma in diabetic patients

作　　者：黄超 刘涛 吴亦文 钟志民 别彩群 朱浩峰 

机构地区：[1]广东省深圳市宝安区沙井人民医院,518104 [2]广东省深圳市光明新区光明中心医院,518107

出　　处：《检验医学与临床》2016年第1期51-52,共2页Laboratory Medicine and Clinic

基　　金：广东省深圳市宝安区卫生局基金资助项目(2014206)

摘　　要：目的探讨直肠异常隐窝病灶(ACF)对糖尿病患者结直肠癌的预警作用。方法回顾性分析486例接受全结肠镜检查和直肠染色放大检查的糖尿病患者的临床资料,分析ACF对结直肠病变发生率的影响。结果 ACF组患者增生性息肉、非进展型腺瘤性息肉、进展型腺瘤性息肉和结直肠癌发生率均明显高于无ACF组,差异有统计学意义(P<0.05)。结论 ACF增加了结直肠癌的发生率,对该类患者应提高警惕,避免漏诊。Objective To explore the prewarning effect of rectal aberrant crypt foci（ACF） for colorectal cancer. Methods 486 cases of diabetes were tested by the total colonoscopy and the rectum dyeing amplification. The in fluence of ACF on the occurrence rate of colorectal lesions was analyzed. Results The occurrence rates of hyperplas tic polyp,non-progress adenomatous polyps, progressive adenomatous polyps and coloreetal carcinoma in the ACF group were significantly higher than those in the non-ACF group, the difference was statistically significant （P〈 0.05）. Conclusion ACF increases the occurrence rate of colorectal carcinoma. These patients should be vigilant for avoiding missed diagnosis.

关 键 词：直肠异常隐窝病灶 结直肠癌 全结肠镜检查 糖尿病 

分 类 号：R282.710.5[医药卫生—中药学]