乳腺癌患者术后抑郁状况调查及危险因素分析  

Investagation of depression status in postoperation patients with breast cancer and analysis of its relationship with risk factors

作　　者：许楠[1] 张鹏彦[1] 周冬仙[1] 刘春红[1] 张雅媛[1] 王元阳 

机构地区：[1]暨南大学附属第二医院(深圳市人民医院)甲状腺外科,广东深圳518020

出　　处：《中国现代医学杂志》2015年第34期68-72,共5页China Journal of Modern Medicine

基　　金：深圳市科技计划项目(No:201102166)

摘　　要：目的调查乳腺癌患者术后的抑郁状况,分析抑郁症状的危险因素。方法应用Beck抑郁量表第2版对205例乳腺癌术后患者进行测评,初步了解乳腺癌患者术后抑郁症状的发生率情况,记录并分析患者一般资料和临床特征相关指标。分别采用t检验和χ2检验对计量资料和计数资料进行分析。危险因素的评估和检测采用单因素和多因素Logistic回归分析。结果该组乳腺癌患者在术后8周时出现抑郁症状的有48例,发生率为23.4%,其中重度抑郁占25%;多因素Logistic回归分析结果显示,低龄（年龄≤45岁）（^OR=2.72,95.0%CI=1.06~7.00）和低收入（收入情况≤7 500元/月）（^OR=3.12,95.0%CI=1.35~7.25）对乳腺癌术后抑郁症状的发生产生影响（P〈0.05）;职业状况、婚姻状态、文化程度、手术方式、临床分期、治疗方式及有无家族史等与乳腺癌抑郁症状无显著性关联。结论术后8周时乳腺癌患者有较高的抑郁症状发生率,低龄和低收入是乳腺癌患者术后抑郁症状发生的危险因素。[Objective]To survey the status of depression in postoperation patients with breast cancer and analyze the relationship between and depressive symptoms and risk factors.[Methods]By using BDI-II, the incidence rate of depressive symptoms of 205 breast cancer patients was screened. The demographic information and clinical features of breast cancer patients were described. The microbiology and related factors were collected and analyzed.T-test, χ2test and Logistic analysis were used to analyze the data,respectively. [Results]The incidence of depressive symptoms in this group of postoperation patients with breast cancer was 23.4%. Among them, severe depressive symptoms accounted for 25%. Multivariate Logistic analysis showed that low age（age ≤ 45 years old）（^OR = 2.72,95.0 % CI = 1.06 ~ 7.00） and Low income（income situation ≤ 7500/month）（^OR = 3.12, 95.0 % CI = 1.35~7.25）were risk factors for depressive symptoms of postoperation breast cancer patients. However, occupational status, marital status, education level, operative method, clinical stage, treatment method, and family history were not associated with depressive symptoms of women with breast cancer.[Conclusion]The incidence rate of depressive symptoms in patients with breast cancer was high, at 8 weeks after operation. Low age and low income are risk factors for depressive symptoms of post-operation breast cancer patients.

关 键 词：乳腺癌 抑郁症状 危险因素 

分 类 号：R655[医药卫生—外科学] R749[医药卫生—临床医学]