心俞穴位注射丹参对冠心病心绞痛患者血浆中ET-1、MDA的影响  

Effects of Danshen Injection at Xinshu Point on the Contents of ET-1 and MDA in Plasma of Patients with Coronary Heart Disease

作　　者：张秋玲[1] 张萍[2] 吕明庄[3] 贺志光[3] 

机构地区：[1]贵州省人民医院针灸科,贵阳550002 [2]贵阳市第四人民医院骨科,550002 [3]贵阳医学院附属医院针灸科,550004

出　　处：《贵州医药》2002年第8期686-687,共2页Guizhou Medical Journal

摘　　要：目的研究心俞穴位注射丹参对冠心病心绞痛患者血浆中ET 1、MDA的影响 ,从而探讨该病发生的体液机制。方法观察 30例冠心病心绞痛患者心俞穴位注射丹参前后血浆中ET 1、MDA的含量 ,与正常对照组作比较。结果冠心病心绞痛患者血浆中ET 1、MDA的含量显著高于正常对照组 (P <0 0 1) ,经心俞穴位注射丹参治疗后显著下降至正常水平 (P <0 0 5或P <0 0 1) ,心绞痛亦有效控治。结论心俞穴位注射丹参可以缓解冠心病心绞痛患者血管内皮细胞损伤或促进其修复抑制脂质过氧化 ,缓解心绞痛。Objective To study the effects of Danshen injection at Xinshu point on the contents of ET 1 and MDA in plasma of patients with coronary heart disease and to explore the humoral mechanism of treatment. Methods The contents of ET 1 and MDA in plasma of 30 patients with coronary heart disease were measured before and after Danshen injection at Xinshu point and the contrasted with that values in normal group. Results The ET 1 and MDA contents in plasma of patients with coronary heart disease were significantly higher than that in normal group before treatment( P <0.01). After treatment, the contents dropped to normal levels and the angina pectoris was alleviated effectively( P <0.01). Conclusion Danshen injection at Xinshu point could remit the impairment of vessel endothelial cells, rehabilitate the injured cells alleviate angina pectoris.

关 键 词：心俞 穴位注射 丹参 心绞痛 ET-1 MDA 

分 类 号：R259.4[医药卫生—中西医结合] R245.95[医药卫生—中医内科学]