不同保温方法对胃癌根治术患者外周血白细胞介素的影响  

Effects of different warming methods on interleukin in peripheral blood for patients undergoing radical gastrectomy

作　　者：邵丽[1] 吐尔洪江.吐逊 贾风菊[1] 颜巧元[3] 

机构地区：[1]新疆医科大学第一附属医院手术室,新疆乌鲁木齐830054 [2]新疆医科大学第一附属医院消化血管外科中心,新疆乌鲁木齐830054 [3]华中科技大学同济医学院附属协和医院护理部

出　　处：《护理学杂志》2015年第24期42-44,共3页

基　　金：国家自然科学基金资助项目(81360082)

摘　　要：目的观察不同保温方法对胃癌手术患者外周血白细胞介素IL-2、IL-6、IL-10的影响,为选取适宜保温方法提供参考。方法将75例胃癌根治术患者随机分为常规保温组(A组)、身体包裹组(B组)、保温毯组(C组)、输液输血加温+身体包裹组(D组)及输液输血加温+保温毯组(E组)五组,在术前(T0)、术后24h(T1)、术后48h(T2)采外周血,检测血浆中IL-2、IL-6、IL-10浓度。结果各组IL-2、IL-6、IL-10血浆浓度在T0、T1、T2呈规律性变化。其中,E组T1时IL-2血浆浓度显著高于其他组,IL-10显著低于其他各组(均P<0.05)。结论不同保温方法对胃癌患者术后IL-2、IL-10浓度有影响,手术过程中采用输液输血加温+保温毯的保温方法有利于维持患者免疫功能。Objective To observe the effects of different warming methods on peripheral blood IL-2,IL-6and IL-10 levels for patients undergoing radical gastrectomy,and to offer reference for selection of suitable warming method.Methods A total of 75 patients undergoing radical gastrectomy were randomized into five groups：routine warming（group A）,body wrapping（group B）,warming blanket（group C）,heated transfusion and body wrapping（group D）,heated transfusion and warming blanket（group E）.Peripheral blood samples were taken before operation（T0）,at 24h（T1）and 48h（T2）after operation for detection of IL-2,IL-6,and IL-10 levels in plasma.Results The plasma levels of IL-2,IL-6,and IL-10 present regular changes from T0,T1 to T2in each group.At T1,the level of IL-2in group E was significantly higher than other groups,while the level of IL-10 in group E was significantly lower than other groups（P〈0.05 for all）.Conclusion Different warming methods affect IL-2and IL-10 levels in plasma for patients undergoing gastrectomy,heated transfusion and warming blanket is conducive to maintain immunologic function for patients.

关 键 词：胃癌根治术 术中保温 棉垫包裹 保温毯 液体加温 包布遮盖 白细胞介素 

分 类 号：R472.3[医药卫生—护理学]