小儿视网膜母细胞瘤的临床及MRI表现  

Clinical and MRI features of retinoblastoma in children

作　　者：陈淑贤[1] 季迅达[2] 曹雯君[1] 夏正荣[1] 李玉华[1] 

机构地区：[1]上海交通大学医学院附属新华医院放射科,上海200092 [2]上海交通大学医学院附属新华医院眼科,上海200092

出　　处：《放射学实践》2015年第12期1169-1172,共4页Radiologic Practice

摘　　要：目的:探讨小儿视网膜母细胞瘤的临床及MRI表现。方法:回顾性分析我院近5年经病理或临床证实的148例(共184眼)儿童视网膜母细胞瘤的临床和MRI资料。结果:148例中男女比例为1.5:1,平均年龄(20.1±16.7)个月;双眼发病36例(24.3%),平均年龄为11.9个月,单眼发病112例,平均年龄为22.8个月。病灶于T1WI上主要为等信号或稍低信号者110眼(92.9%);T2WI上以等信号为主者97眼(52.7%),其余病灶表现为稍低、稍高或混杂信号;增强扫描示病灶以轻度或中度强化为主(174/178,97.8%);DWI上病灶主要表现为显著高信号(91.3%),ADC值为0.939×10^(-3)±0.225×10^(-3) mm2/s。结论:视网膜母细胞瘤的MRI表现具有一定的特征性,MRI尤其是DWI对本病的诊断具有重要价值。Objective：To investigate the clinical presentations and MRI features of retinoblastoma （RB） in children. Methods：The clinical and MRI data of 148 cases （184 eyes） of retinoblastoma in children confirmed by clinical findings or pathology in our hospital in recent 5 years were analyzed retrospectively. Results： In total 148 cases, the male to female ratio was 1.5 ： 1, the mean age was （20.1 ± 16.7） months. The tumors were bilateral in 36 cases （24.3 % ）, in which the mean age was 11.9 months,and in unilateral cases （112 cases） that was 22.8 months. The main MRI findings of the tumors included： slight hypo-intensity or iso intensity on T1WI in 110 eyes （92. 9%）, iso-intensity on T2WI in 97 eyes （52. 7%）, mild or moderate enhancement on contrast-enhanced T1 WI in 174 eyes （ 174/178,97.8 % ）, and obvious hyper-intensity on DWI, with the apparent diffusion coefficient （ADC） value of （0. 939 × 10-3±0. 225 ×10-3 ）mm2/s. Conclusion： MRI findings of retinoblastoma have certain characteristics and DWI olavs an important role in diagnosis.

关 键 词：磁共振成像 扩散加权成像 视网膜母细胞瘤 儿童 

分 类 号：R445.2[医药卫生—影像医学与核医学]