青岛地区中老年人膝骨关节炎流行病学研究  

Epidemiological investigation of knee osteoarthritis in middle-aged and senior residents in district of Qingdao

作　　者：田少奇[1] 王斌[2] 孙康[1] 王远贺[1] 刘论[1] 哈承志[1] 王荣[1] 潘丕春[1] 李启才[1] 石祥龙[3] 杨志涛[3] 侯庆先[4] 

机构地区：[1]青岛大学附属医院关节外科,266000 [2]青岛市第三人民医院骨科,266000 [3]青岛大学附属医院放射科,266000 [4]青岛大学附属医院脊柱外科,266000

出　　处：《中华关节外科杂志（电子版）》2015年第6期65-69,共5页Chinese Journal of Joint Surgery(Electronic Edition)

基　　金：国家自然科学基金委员会主任基金(81141078);青岛大学附属医院青年科研基金

摘　　要：目的了解青岛地区中老年人膝关节骨关节炎(KOA)的患病率并探讨其相关危险因素。方法按照分层、多阶段、整群随机抽样的原则,抽取青岛地区(包括市区及农村本地)具有当地正式户口的40岁及以上居民进行KOA的流行病学问卷调查、专科查体和拍摄X线片,非青岛地区的本地户口、年龄40岁以下及不签署知情同意的人员则排除在本调查研究以外。采用Logistic回归分析,观察性别、年龄、身体质量指数(BMI)、受教育程度、职业类型、居住楼层、饮食习惯等因素对KOA的影响。结果临床KOA患病率为14.7%,其中女性为20.3%,男性为8.5%,女性患病率显著高于男性,且有随年龄增加而有升高的趋势。KOA组BMI显著大于非KOA组。临床KOA患病率在城乡方面未发现统计学差异。Logistic回归分析结果显示:年龄、性别、BMI、受教育程度低、重体力劳动、居住无电梯高楼层、非清淡饮食等为KOA的危险因素。结论青岛地区中老年人KOA患病率较高,应引起足够的重视。年龄、性别、BMI、受教育程度、职业类型、爬楼梯、饮食习惯等与KOA有关。Objective To investigate the prevalence of knee osteoarthritis（ KOA） associated risk factors in middle aged and senior residents in district of Qingdao. Methods The urban and rural residents aged 40 years old and above were investigated by questionnaire,the people who were less than 40 years old,non-residents and denied to accept the informed consent were excluded. Special course physical examination and radiographic examination were performed by stratification and multiple stage cluster sampling. Variables such as sex,age,body mass index（ BMI）,educational level,occupation type,residential floor height and dietary habit were included in binary logistic regression model for further analysis. Results The total prevalence of clinical KOA was 14. 7%,and 20. 3% in women and 8. 5% in men. The prevalence of KOA in women was significantly higher than that in men,and with a tendency of increasing with age. BMI in KOA group was significantly higher than that in non-KOA group. No significant difference was found when comparing the prevalence of clinical KOA between urban and rural residents. Binary logistic regression revealed that age,sex,BMI,educational level,occupation type,residential floor height and dietary habit were significantly associated with KOA. Conclusions The prevalence of KOA is high in the middle aged and senior residents in the district of Qingdao,which should be paid enough attention to. The factors including age,sex,BMI,educational level,occupation type,residential floor height and dietary habit may be associated with KOA.

关 键 词：骨关节炎 膝 流行病学研究 患病率 危险因素 

分 类 号：R684.3[医药卫生—骨科学]