首次早期妊娠妇女血清孕酮与妊娠结局的相关性  

First Trimester Pregnancy Outcomes of Women With Serum Progesterone Correlation

作　　者：梁瑞 苏国生[2] 黄志官 潘莲花[2] 

机构地区：[1]广西百色市中医院检验科,广西百色533000 [2]广西南宁市第四人民医院,广西艾滋病临床治疗中心(南宁),广西南宁530023

出　　处：《黑龙江医药》2015年第5期1038-1040,共3页Heilongjiang Medicine journal

基　　金：广西南宁市科学技术与研究计划项目(NO.201106048C-2)

摘　　要：目的：了解首次早期妊娠妇女血清孕酮与妊娠结局的关系。方法：选取250例妇科门诊确诊的首次早期妊娠的妇女,按血清孕酮浓度的不同分为3组,①组孕酮值〉78 nmol/L,②组孕酮值31.8～78 nmol/L,③组孕酮值〈31.8 nmol/L,分别进行血清孕酮的检查,随访跟踪,对其妊娠结局进行统计分析。结果：250例中,血清孕酮〉78 nmol/ml 110例,其中正常妊娠102例,占92.73%,流产7例,占6.36%,异位妊娠1例,占0.91%;血清孕酮值31.8～78 nmol/ml 85例,其中正常妊娠68例,占80%,流产13例,占15.29%,异位妊娠4例,占4.71%;血清孕酮〈31.8 nmol/ml 55例,其中正常妊娠32例,占49.23%,流产15例,占23.08%,异位妊娠8例,占12.13%。三组正常妊娠率比较,差异均有显著统计学意义（P〈0.01）,进一步两两比较发现,①组正常妊娠率高于②组和③组,②组正常妊娠率高于③组,即血清孕酮浓度水平逐步降低,正常妊娠率随之下降,异常妊娠（包括流产和异位妊娠）的发生率随之上升。结论：首次早期妊娠妇女血清孕酮浓度与妊娠结果密切相关,血清孕酮浓度越低,妊娠妇女越容易流产或异位妊娠。因此在妊娠期间不定时进行血清孕酮的检测有利于动态观察胎儿的发育情况。Objective：To understand the relationship between serum progesterone first trimester women with pregnancy outcome.Methods：250 cases diagnosed in the first gynecological clinic for women in early pregnancy,according to different serum progesterone concentrations were divided into three groups,①group progesterone values〉 78 nmol / L,②group progesterone 31.8～78 nmol /L,③group progesterone values〈 31.8 nmol/L,serum progesterone checked,the follow-up track;and retrospective statistical analysis of their pregnancy outcome.Results：250 cases,the serum progesterone 〉78 nmol/ml 110 cases,including 102 cases of normal pregnancy,accounting for 92.73%,abortion seven cases,accounting for 6.36%,one case of ectopic pregnancy,accounting for 0.91%;31.8serum progesterone values～78 nmol/ml 85 cases,including 68 cases of normal pregnancy,accounting for 80 percent,abortion 13 cases,accounting for 15.29%,4 cases of ectopic pregnancy,accounting for 4.71%;serum progesterone〈 31.8 nmol/ml 55 cases,including normal pregnancy 32 cases,accounting for 49.23%,abortion 15 cases,accounting for 23.08%,8 cases of ectopic pregnancy,accounting for 12.13%.Three groups of normal pregnancy,the difference was statistically significant（P〈0.01）,further pairwise comparisons found that,①group of normal pregnancy rate higher than②,③group,②③group higher than normal pregnancy group（P〈0.01）,namely serum progesterone levels gradually decreased,normal pregnancy fall,abnormal pregnancy（including miscarriage and ectopic pregnancy） incidence rise.Conclusion：The first women in early pregnancy serum progesterone concentration is closely related to pregnancy outcomes,lower serum progesterone concentrations in pregnant women more likely to miscarriage or ectopic pregnancy.So from time to time during pregnancy to detect serum progesterone in favor of dynamic observation of fetal development.

关 键 词：孕酮 妊娠结局 异位妊娠 流产 

分 类 号：R714[医药卫生—妇产科学]