五省市部分放射工作人员体检白细胞计数分析  

Ananlysis on Leucocyte of Radiation Workers in the Selected Health Checkup Institutions

作　　者：程晓青[1] 赵世义[2] 李洁清[3] 吴艳延 陈维[5] 林海辉[6] 雷淑洁[1] 傅颖华[1] 李小娟[1] 孙全富[1] 

机构地区：[1]中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室,北京100088 [2]天津市职业病防治院 [3]山东省医学科学院放射医学研究所 [4]河南省职业病防治院 [5]江苏省疾病预防控制中心 [6]广东省职业病防治院

出　　处：《中国辐射卫生》2015年第2期97-100,共4页Chinese Journal of Radiological Health

基　　金：卫生行业科研专项项目(201002009)

摘　　要：目的比较不同放射工作人员的白细胞水平与一般人群的差异,并探索可能的影响因素。方法采用五个省(市)2011年、2012年和2013年的放射工作人员健康体检数据,与一般人群白细胞计数正常值进行比较,采用单因素分析和多元线性回归分析的方法,研究不同因素对放射工作人员白细胞计数的影响。结果本研究确认符合要求的研究对象共7314人,其中男性5595人(76.50%),女性1719人(23.50%),平均年龄为(37.71±10.14)岁,白细胞计数均值为(6.29±1.60)×109/L,一般人群白细胞计数为(6.50±1.53)×109/L,放射工作人员白细胞计数较一般人群低3.23%,差异有统计学意义(P<0.001)。女性的白细胞计数低于男性,且在年龄小于50岁的人群中,白细胞计数有随年龄增加而减少的趋势,差异均有统计学意义(P<0.05)。不同省市体检机构的放射工作人员白细胞计数也不同,且差异有统计学意义(P<0.05)。多元线性回归分析结果显示,在调整年龄、性别和地区因素后,不同职业照射类别人员的白细胞计数之间的差异无统计学意义(P>0.05)。结论放射工作人员白细胞计数在正常医学参考值范围内,但低于一般人群,可能与性别、年龄和不同地区体检机构之间的差异有关,尚不能认为与职业照射类别有关,需要进一步研究。Objective To investigate the physical condition of radiation workers by analyzing their leucocyte and try to identify major influential factors associated with their leucocyte.Methods Physical examination data of radiation workers in the selected health checkup institutions in 2011,2012 and 2013 were analyzed and compared with that general population.Single factor analysis and multiple linear regression analysis were used for statistical analysis.Results This study collected 7314 effective physical examine data.They were from 5595（76.50%） male and 1719（23.50%） female.The average age was（37.71 ± 10.14） and the mean of leucocyte was（6.29 ± 1.60） × 10^9/ L.Leucocyte mean of average population is（6.50 ±1.53） × 10^9/ L.According to analysis,the leucocyte level of the subjects was 3.23% statistically lower than those of average population（P〈 0.001）.The leucocyte mean of female was not as high as that of male.Among people under the age of 50,leucocyte level of elder people tended to be statistically lower than that of the younger ones（P〈0.05）.Difference among provinces（city） were statistically different（P〈0.05）.No statistical significance was found among different work types after adjusted by age,gender and district factors（P〉0.05）.Conclusion Leucocyte level of radiation workers was within the medical reference range,but lower than average people.Gender,age and district related factors maybe influential.Whether work type is an influential factor or not needed further research.

关 键 词：放射工作人员 健康体检 白细胞 

分 类 号：Q691[生物学—生物物理学]