心率血压乘积对右锁骨下动脉斑块检出率的影响  

The Influence of Rate-pressure Product on Detection Rate of Right Subclavian Artery Plaque

作　　者：王义[1] 高新颖[2] 赵晓红[3] 崔凯[3] 吴云涛[3] 董岩[2] 阮春雨[3] 赵海燕[3] 魏国清[3] 金城[3] 吴寿岭[3] 

机构地区：[1]开滦总医院马家沟医院 [2]开滦总医院林西医院心内科 [3]开滦总医院心内科,河北省唐山市063000

出　　处：《中国动脉硬化杂志》2015年第8期795-801,共7页Chinese Journal of Arteriosclerosis

基　　金：国家科技重大专项课题(2008ZX09312-008-004)

摘　　要：目的探讨心率血压乘积（RPP）对右锁骨下动脉斑块检出率的影响。方法采用横断面研究设计,在2006年至2007年参加健康体检的101510例开滦集团职工中随机分层抽取5852例作为研究对象,进行统一问卷调查、血液生化及颈动脉彩超检查,符合入选标准的（年龄≥40岁、既往无脑卒中及短暂性脑缺血发作、心肌梗死者）为5440例,资料完整的5154例纳入统计分析。依据2010-2011年度体检时RPP四分位数将研究对象分为RPP〈7707、7707≤RPP〈8970、8970≤RPP〈10401、RPP≥10401四组,用多因素Logistic回归分析RPP对右锁骨下动脉斑块检出率的影响。结果 （1）5154例研究对象（男性3100例,女性2054例）的平均年龄为54.83岁;（2）右锁骨下动脉斑块检出率为33.1%,四组右锁骨下动脉斑块检出率分别为27.1%、30.4%、35.1%和39.8%;（3）影响右锁骨下动脉斑块检出率的多因素Logistic回归分析显示：校正了年龄、性别等因素后,与RPP第一分位组比较,第三及第四分位组检出斑块的风险仍增加,其0R值分别为1.22（95%CI 1.01-1.47）和1.28（95%CI 1.05-1.55）。结论 RPP增高增加右锁骨下动脉斑块的检出风险。Aim To investigate the influence of rate-pressure product（ RPP） on right subclavian artery plaque detection rate. Methods A total of 5852 participants were selected with stratified random sampling from the 101510 workers of Tangshan Kai Luan company who received the health examination. 5154 of them with integral data were recruited into the survey. The observation population was divided into four groups according to RPP collected during 2010 ~2011 health examinations： quartile 1（ RPP 〈7707）,quartile 2（ 7707≤RPP 〈8970）,quartile 3（ 8970≤RPP 10401）,quartile 4（ RPP≥10401）. Multivariate logistic regression analysis was used to analyze the influence of RPP on detection rate of right subclavian artery plaque. Results（ 1） The study included 5154 participants（ male 3100 cases,female2054 cases） with a mean age of 54. 83 years.（ 2） The right subclavian artery plaque detection rate was 33. 1%. The right subclavian artery plaque detection rate for the above quartiles of RPP were 27. 1%,30. 4%,35. 1% and 39. 8%,respectively.（ 3） After adjusting for confounding parameters such as age,gender and other risk factors,multiple logistic regression analysis showed that the risk of detection of right subclavian artery plaque was increased in quartile 3 and 4 of RPP compared with quartile 1,and the OR values were 1. 22（ 95% CI 1. 01 ~ 1. 47） and 1. 28（ 95% CI 1. 05 ~ 1. 55）,respectively. Conclusion Increased RPP increase the detection risk of right subclavian artery plaque.

关 键 词：心率血压乘积 右锁骨下动脉斑块 检出率 

分 类 号：R5[医药卫生—内科学]