尿液中微量元素水平与儿童肥胖相关性分析  

Relationship between urinary trace elements levels and obesity children

作　　者：邱金丽[1] 宋媛[2] 褚兰玲[1] 刘萍[2] 黄晶晶[1] 赵仁山 康学军[1] 葛芹玉[1] 

机构地区：[1]东南大学学习科学研究中心儿童发展与学习科学教育部重点实验室,南京210096 [2]苏州市立医院儿童保健科,苏州215002

出　　处：《微量元素与健康研究》2016年第1期23-25,共3页Studies of Trace Elements and Health

基　　金：江苏省妇幼保健科研项目(F201303)

摘　　要：目的：探讨学龄前儿童体内微量元素水平与其肥胖之间的关系。方法：以苏州市某幼儿园5~7岁儿童为研究对象,通过测量身高、体质量、BMI指数（包括父母亲）筛选出肥胖儿童,共29人,并选取31名正常儿童作为对照组,检测其尿液中的微量元素含量。利用SPSS17.0软件进行差异性检验和相关性分析。结果：两组儿童微量元素水平差异极其显著（P=0.00）,其中肥胖儿童尿液中Fe、Zn、Cu的水平分别为27.9±12.4μg/dl,41.4±21.5μg/dl,1.8±0.6μg/dl,均远远低于对照组（分别为83.7±21.6μg/dl,86.5±19.0μg/dl,51.9±3.9μg/dl）,并且其尿液中Fe、Zn、Cu的水平与其BMI指数呈负相关（r〈0）。肥胖儿童BMI指数与其父母亲的BMI指数均呈正相关。Objective： To determine urinary trace elements levels in children with and without obesity,and to assess if trace elements influence the risk of obesity. Another purpose of this paper is to examine the relationship between levels of trace elements and body mass index（ BMI）. Methods： Inductively coupled plasma mass spectrometry（ ICP- MS） was used to determine the contents of Fe,Zn,Cu in 60 children（ age 5 ~ 7： 29 obese children,31 no- obese children）. Independent t test was applied to assess the difference of trace elements contents in samples. Correlations between variables were tested with the use of Pearson＇s correlation coefficient. Result： Obese children had lower Fe,Zn,Cu contents,the values of them were 27. 9 ± 12. 4 μg/dl,41. 4 ± 21. 5 μg/dl and 1. 8 ± 0. 6 μg/dl. Fe,Zn,Cu contents in urine（ P = 0. 00） were the independent factors significantly influencing the risk of obesity in children. The values of BMI for children had positive correlation with their mothers＇ BMI values（ 0 r 1） and they were negatively related to the levels of Fe,Zn,Cu（ r 0）. The decreasing level of trace elements was associated with obesity.

关 键 词：儿童 肥胖 尿液 微量元素 

分 类 号：R723.14[医药卫生—儿科]