不同免疫状态下侵袭性肺曲霉菌病的CT表现  

CT characteristics of invasive pulmonary aspergillosis in patients with different immune status

作　　者：周嘉璇[1] 曾庆思[1] 陈淮[1] 李娴[1] 刘琴[1] 黄晓燕[1] 王寿扬[1] 黎剑宇[1] 

机构地区：[1]广州医科大学附属第一医院放射科,广东广州510120

出　　处：《中国医学影像技术》2016年第1期63-66,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨不同免疫状态下侵袭性肺曲霉菌病CT表现的特征。方法回顾性分析本院诊断为侵袭性肺曲霉菌病的免疫异常组(n=29)和免疫正常组(n=10)侵袭性肺曲霉菌病患者的CT表现。结果免疫异常组和免疫正常组单发病灶[3.45%(1/29)、30.00%(3/10)]、实变影[82.76%(24/29)、40.00%(4/10)]、小叶间隔增厚[51.72%(15/29)、10.00%(1/10)]、胸腔积液[58.62%(17/29)、10.00%(1/10)]比较差异均有统计学意义(P均<0.05);磨玻璃影、结节、团块影、空洞、空洞分隔征、晕征、树芽征、支气管扩张、侵袭类型比较,差异均无统计学意义(P均>0.05)。结论不同免疫状态下侵袭性肺曲霉菌病的CT表现有一定的差异。多发结节伴晕征、实变影、磨玻璃影、空洞及空洞分隔征等CT征象对提高侵袭性肺曲霉菌病的诊断具有重要意义。Objective To evaluate the CT characteristics of invasive pulmonary aspergillosis（IPA）in patients with different immune status.Methods IPA patients were devided into Immunocompetent group（n=10）and immunocompromised group（n=29）.The CT features were analyzed retrospectively.Results Comparing immunocompromised group with immunocompetent group,there were statistical differences in the occurence of single lesion（3.45% [1/29]vs 30.00% [3/10]）,consolidations（82.76% [24/29]vs 40.00% [4/10]）,thickened interlobular septal（51.72% [15/29]vs 10.00%[1/10]）and pleural effusion（58.62% [17/29]vs 10.00% [1/10],all P〈0.05）.But statistical differences were not observed on the occurence of ground glass opacity,nodules,mass,cavity and linear space sign in cavity,halo sign,tree in bud sign,bronchiectasis and invasive types（all P〉0.05）.Conclusion CT characteristics of IPA are different in patients with different immune status.Multiple nodules or centrilobular micronodules with halo sign,consolidations,ground glass opacity,cavity and linear space sign in cavity are characteristics which could improve IPA diagnosis.

关 键 词：曲霉菌 体层摄影术 X线计算机 免疫状态 

分 类 号：R563[医药卫生—呼吸系统] R814.42[医药卫生—内科学]