三伏贴治疗变应性鼻炎近期疗效及不良反应的观察  

Short effect and adverse reaction of dog days plaster for allergic rhinitis

作　　者：张红丽[1] 赵铭辉[2] 傅立新[3] 

机构地区：[1]天津中医药大学,天津300073 [2]天津中医药大学第一附属医院耳鼻喉科,天津300193 [3]天津中医药大学第一附属医院针灸科,天津300193

出　　处：《中国针灸》2016年第1期33-36,共4页Chinese Acupuncture & Moxibustion

基　　金：天津市中医药管理局课题项目:13077

摘　　要：目的：评价＂三伏天＂穴位贴敷治疗变应性鼻炎的近期疗效与安全性。方法：将249例患者随机分为三伏贴组（166例）、安慰剂组（83例）。于三伏天初、中、末伏的第一天开始进行穴位贴敷,穴取大椎、肺俞、脾俞、肾俞为主,三伏贴组采用中药（白芥子、细辛、延胡索、甘遂）穴位贴敷,安慰剂组采用非药物成分的荞麦粉进行贴敷,每次贴敷时间2~6h,每伏的头三天连续贴敷,患者连续贴敷满三伏为一疗程。观察两组患者治疗前及治疗1个疗程后的症状、体征积分、症状视觉模拟量表（VAS）评分变化和治疗期间的不良反应及处理情况。结果：两组治疗后的症状、体征积分及症状VAS评分均较治疗前改善（均P〈0.05）,且治疗后三伏贴组对以上评分的改善优于安慰剂组（均P〈0.05）。三伏贴组近期总有效率为68.1%（113/166）,优于安慰剂组的48.2%（40/83,P〈0.05）;三伏贴组不良反应发生率为4.2%（7/166）,安慰剂组为2.4%（2/83）,但组间差异无统计学意义（P〉0.05）。结论：＂三伏贴＂治疗变应性鼻炎近期疗效显著,且安全性良好。Objective To evaluate the short effect and safety of the acupoint application of dog days for allergic rhinitis.Methods Two hundred and forty-nine patients were randomly divided into an application group（166 cases）and a placebo group（83 cases）.On the first day of the first dog days,the first day of the second of the three ten-day periods of the hot season and the first day of the last of the three ten-day periods of the hot season,acupoint application was adopted mainly at Dazhui（GV 14）,Feishu（BL 13）,Pishu（BL 20）and Shenshu（BL 23）in the application group.The plaster was made of Chinese herbs,including Baijiezi（semen brassicae）,Xixin（asarum）,Yanhusuo（corydalis tuber）and Gansui（euphorbia kansui）.Buckwheat plaster without medical ingredient was used in the placebo group.The application was pasted for 2-6 hevery time.On the first three days of all the three periods of dog days,treatment was used continuously.The whole period of dog days was made into one course.The changes of symptom and syndrome scores,visual analogue scale（VAS）for symptom before and after treatment and the adverse reaction with the condition disposed were observed in the two groups.Results After treatment,the symptom and syndrome scores and VAS for symptom were improved compared with those before treatment in the two groups（all P〈0.05）,and the improvements of the application group were more obvious than those of the placebo group（all P〈0.05）.The short effective rate of the application group was 68.1%（113/166）,which was better than 48.2%（40/83）of the placebo group（P〈0.05）.The adverse reaction rates were 4.2%（7/166）,2.4%（2/83）respectively,with no statistical significance between the two groups（P 〉0.05）.Conclusion The dog days plaster achieves obvious effect with good safety for allergic rhinitis.

关 键 词：变应性鼻炎 三伏贴 近期疗效 安全性 随机对照试验 

分 类 号：R246.8[医药卫生—针灸推拿学]